B3306

Bisindolylmaleimide IV

≥98% (TLC), solid

• Synonim(y): Ro 31-6233
• Wzór empiryczny (zapis Hilla): C₂₀H₁₃N₃O₂
• Numer CAS: 119139-23-0
• Masa cząsteczkowa: 327.34
• NACRES: NA.77
• PubChem Substance ID: 24891709
• UNSPSC Code: 12352111
• MDL number: MFCD00236432
• Assay: ≥98% (TLC)
• Form: solid

Właściwości

• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: solid
• color: dark red
• solubility: DMSO: soluble, methanol: soluble
• storage temp.: −20°C
• SMILES string: O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c4c[nH]c5ccccc45
• InChI: 1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
• InChI key: DQYBRTASHMYDJG-UHFFFAOYSA-N
• Gene Information: human ... CDK2(1017), EGFR(1956) ; rat ... Prkca(24680)

Opis

Biochem/physiol Actions

Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI.[1] BIMs act as an inhibitor of protein kinase C (PKC).[1] They are derived from staurosporine.[2] BIM IX due to its proapoptotic functionality could be useful in targeting tumor proliferation.[3]

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)