A7980

AC-41848 hydrate

≥98% (HPLC), solid

• Synonim(y): 1-[(2,4-Dichlorophenyl)methyl]-6,7,8,9-tetrahydro-3-phenyl-5H-imidazo[1,2-a]azepinium bromide hydrate
• Wzór empiryczny (zapis Hilla): C₂₁H₂₁BrCl₂N₂ · xH₂O
• Numer CAS: 400856-69-1
• Masa cząsteczkowa: 452.21 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 24724399
• UNSPSC Code: 12352200
• MDL number: MFCD08705316
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100
• Storage condition: desiccated, under inert gas

Właściwości

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated, under inert gas
• solubility: DMSO: ~14 mg/mL, H₂O: >5 mg/mL
• storage temp.: 2-8°C
• SMILES string: [Br-].[H]O[H].Clc1ccc(C[n+]2cc(-c3ccccc3)n4CCCCCc24)c(Cl)c1
• InChI: 1S/C21H21Cl2N2.BrH.H2O/c22-18-11-10-17(19(23)13-18)14-24-15-20(16-7-3-1-4-8-16)25-12-6-2-5-9-21(24)25;;/h1,3-4,7-8,10-11,13,15H,2,5-6,9,12,14H2;1H;1H2/q+1;;/p-1
• InChI key: FPOBEBBUBSFIIA-UHFFFAOYSA-M

Opis

Application

AC-41848 is a potent, cell permeable, and subtype selective retinoic acid receptor RARγ agonist.

Biochem/physiol Actions

AC-41848 is a potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. AC-41848 has high selectivity (92%) for RARγ. EC₅₀ = 5.9 μM.

Potent, cell permeable, subtype selective retinoic acid receptor RARγ agonist. High selectivity (92%) for RARγ. EC₅₀ = 5.9 μM.

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves