A6419

Adenosine 5′-triphosphate disodium salt hydrate

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• Synonim(y): ATP disodium salt
• Wzór empiryczny (zapis Hilla): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• Numer CAS: 34369-07-8
• Masa cząsteczkowa: 551.14 (anhydrous basis)
• Numer MDL: MFCD00150755
• Kod UNSPSC: 12352207
• eCl@ss: 32160414
• Identyfikator substancji w PubChem: 24891086
• NACRES: NA.75

Właściwości

• pochodzenie biologiczne: microbial
• Poziom jakości: 200
• linia produktu: BioReagent
• Próba: ≥99% (HPLC)
• Postać: powder
• metody: cell culture | mammalian: suitable
• rozpuszczalność: H₂O: 50 mg/mL
• temp. przechowywania: −20°C
• ciąg SMILES: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Klucz InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Opis

Opis ogólny

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Zastosowanie

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

Działania biochem./fizjol.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Faceshields, Gloves, type N95 (US)