A3286

N-Acetyl-D-glucosamine

BioReagent, suitable for cell culture

• Synonim(y): 2-Acetamido-2-deoxy-D-glucose, D-GlcNAc
• Wzór empiryczny (zapis Hilla): C₈H₁₅NO₆
• Numer CAS: 7512-17-6
• Masa cząsteczkowa: 221.21
• UNSPSC Code: 12352201
• NACRES: NA.75
• PubChem Substance ID: 24890757
• EC Number: 231-368-2
• Beilstein/REAXYS Number: 1727589
• MDL number: MFCD00061615

Właściwości

• product line: BioReagent
• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 211 °C (dec.) (lit.)
• application(s): advanced drug delivery
• storage temp.: −20°C
• SMILES string: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• InChI key: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Opis

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.[1]

Application

N-Acetyl-D-glucosamine addition has been used:

• as a substrate to develop dot-blots
• as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis[1]
• to detect specific immune complexes in western blot analysis

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity. GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.[1]

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)