Przejdź do zawartości
Merck

Przejdź do

90469

(RS)-Mevalonic acid lithium salt

≥96.0% (GC)

Synonim(y):

(±)-MVA-Li, rac.-MVA-Li, Lithium (±)-3,5-dihydroxy-3-methyl-pentanoate, Lithium (±)-3,5-dihydroxy-3-methyl-valerate

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

Zmień widok
Gabaryty przesyłkiSKUDostępnośćCena netto
10 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
678,00 zł
50 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
2690,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C6H11O4 · xLi+
Numer CAS:
Masa cząsteczkowa:
147.15 (free acid basis)
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.25
Assay:
≥96.0% (GC)
Form:
solid

678,00 zł


Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności

Zamów zamówienie zbiorcze
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomóc


Quality Level

assay

≥96.0% (GC)

form

solid

composition

lithium, 2.2-4.7%

storage temp.

2-8°C

SMILES string

OC(CCO)(CC(=O)O)C

InChI

1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9)

InChI key

KJTLQQUUPVSXIM-UHFFFAOYSA-N

Biochem/physiol Actions

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja
447144214743987
form

solid

form

-

form

-

form

-

assay

≥96.0% (GC)

assay

≥96.0% (GC)

assay

≥96.0% (GC)

assay

≥97.0% (GC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

composition

lithium, 2.2-4.7%

composition

-

composition

-

composition

-


Still not finding the right product?

Explore all of our products under


Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

Nie widzisz odpowiedniej wersji?

Jeśli potrzebujesz konkretnej wersji, możesz wyszukać konkretny certyfikat według numeru partii lub serii.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Ai Hosaka et al.
Neurochemical research, 38(3), 589-600 (2012-12-28)
Statins, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, have been reported to attenuate amyloid-β peptide (Aβ) production in various cellular models. However, the mechanisms by which statins affect neuronal Aβ production have not yet been clarified. Here, we investigated this issue in
Martin Thurnher et al.
Biochimica et biophysica acta, 1831(6), 1009-1015 (2013-03-26)
The mevalonate pathway is a highly conserved metabolic cascade and provides isoprenoid building blocks for the biosynthesis of vital cellular products such as cholesterol or prenyl pyrophosphates that serve as substrates for the posttranslational prenylation of numerous proteins. The pathway
Elena Lesma et al.
The Journal of pharmacology and experimental therapeutics, 345(2), 180-188 (2013-02-22)
Tuberous sclerosis complex (TSC) is a multi-systemic syndrome caused by mutations in TSC1 or TSC2 gene. In TSC2-null cells, Rheb, a member of the Ras family of GTPases, is constitutively activated. Statins inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase and block the



Numer pozycji handlu globalnego

SKUNUMER GTIN
90469-10MG04061832393810
90469-250MG04061832393827
90469-50MG04061832393834

Questions

1–5 of 5 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. can you confirm the RS isomer relative composition of the mixed isomer product 90469?

    1 answer
    1. The compound is labeled as (±) or racemic meaning there are an equal mix of R and S isomers. However, there are no optical activity assays performed on the final product to verify the exact compositions of the R and S isomers.

      Helpful?

  4. Is there any information available regarding the solubility of (RS)-Mevalonic acid lithium salt, Catalog 90469, for resuspension purposes?

    1 answer
    1. The solubility of (RS)-Mevalonic acid lithium salt is as follows:
      1. In H2O: 100 mg/mL (648.97 mM; ultrasonic agitation required)
      2.In DMSO: 50 mg/mL (324.49 mM; ultrasonic agitation required)

      Helpful?

  5. What is the recommended solution to dissolve this product in if wanting to add to cell culture media?

    1 answer
    1. This product is not tested for solubility. However various sources state that compound is soluble in water and PBS (may require sonication), as well as DMSO.

      Helpful?

Reviews

No rating value

Active Filters