68224

N-Dodecanoyl-L-homoserine lactone

≥96% (HPLC), suitable for mass spectrometry (MS)

• Synonim(y): N-Lauroyl-L-homoserine lactone, N-[(3S)-Tetrahydro-2-oxo-3-furanyl]dodecanamide, C12-HSL
• Wzór empiryczny (zapis Hilla): C₁₆H₂₉NO₃
• Numer CAS: 137173-46-7
• Masa cząsteczkowa: 283.41
• NACRES: NA.28
• PubChem Substance ID: 329760775
• UNSPSC Code: 12352211
• MDL number: MFCD11976890
• Beilstein/REAXYS Number: 9281984

Właściwości

• Nazwa produktu: N-Dodecanoyl-L-homoserine lactone, ≥96% (HPLC)
• Quality Segment: 100
• assay: ≥96% (HPLC)
• form: powder or crystals
• optical activity: [α]/D -25±5°, c = 0.2 in methanol
• technique(s): mass spectrometry (MS): suitable
• color: white to off-white
• suitability: conforms to structure for Proton NMR spectrum
• storage temp.: −20°C
• SMILES string: O=C1OCC[C@@H]1NC(CCCCCCCCCCC)=O
• InChI: 1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
• InChI key: WILLZMOKUUPJSL-AWEZNQCLSA-N

Opis

Biochem/physiol Actions

N-Dodecanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see[1][2][3][4][5]. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs[3], and a research focus for the prevention of biofilm formation[6][7][8].

Quorum-sensing signal generation

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Informacja o środkach bezpieczeństwa

• hcodes: H413
• Hazard Classifications: Aquatic Chronic 4
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable