90970

γ-Butyrolactone

analytical standard

• Synonim(y): γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
• Wzór empiryczny (zapis Hilla): C₄H₆O₂
• Numer CAS: 96-48-0
• Masa cząsteczkowa: 86.09
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329769980
• EC Number: 202-509-5
• Beilstein/REAXYS Number: 105248
• MDL number: MFCD00005386

Właściwości

• grade: analytical standard
• Quality Segment: 100
• vapor density: 3 (vs air)
• vapor pressure: 1.5 mmHg ( 20 °C)
• assay: ≥99.0% (GC)
• autoignition temp.: 851 °F
• shelf life: limited shelf life, expiry date on the label
• expl. lim.: 16 %
• drug control: Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• impurities: ≤0.3% water
• refractive index: n20/D 1.436 (lit.)
• bp: 204-205 °C (lit.)
• mp: −45 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChI key: YEJRWHAVMIAJKC-UHFFFAOYSA-N

Opis

General description

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc.

Application

γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Precursor of γ-hydroxybutyric acid (GHB); blocks dopamine release.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318,H336
• pcodes: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• target_organs: Central nervous system
• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: 208.4 °F - closed cup
• flash_point_c: 98 °C - closed cup