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69479

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

derivatization grade (GC derivatization), LiChropur, ≥98.5%

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Synonim(y):

N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA

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Gabaryty przesyłkiSKUDostępnośćCena netto
5 mL
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1360,00 zł
10 x 1 mL
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2730,00 zł
25 mL
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3730,00 zł

Informacje o tej pozycji

Wzór liniowy:
CF3CON(CH3)Si(CH3)3
Numer CAS:
Masa cząsteczkowa:
199.25
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
EC Number:
246-331-6
Beilstein/REAXYS Number:
1941550
MDL number:
Assay:
≥98.5% (GC), ≥98.5%
Form:
liquid

1360,00 zł


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grade

derivatization grade (GC derivatization)

Quality Segment

vapor density

>1 (vs air)

vapor pressure

8.8 mmHg ( 27 °C)

assay

≥98.5% (GC), ≥98.5%

form

liquid

quality

LiChropur

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.38 (lit.), n20/D 1.380

bp

130-132 °C (lit.)

density

1.075 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

General description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylating reagent.[1]

Application

Learn more in the Product Information
MSTFA may be used in silylation procedure to detemine steroid hormones 17α-ethinylestradiol (EE2) and estrone using GC-MS. MSTFA along with Trimethylsilyl chloride (TMCS) in eithyl acetate, acetonitrile and dichloromethane solvents leads to formation of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBS) derivatives.[1]
Suitable for the derivatization of amines, amino acids, carboxyl, hydroxyamines, indolalkylamine, n-nitrosoamino acids, nucleosides, phenolalkylamines, serotonin and tryptamine.

Other Notes

Reagent for N-acetyl-N, trifluoroacetyl, trimethylsilyl, N-trimethylsilyl-N-trifluoroacetyl, and O-trimethylsilyl (TMS)
Powerful silylating agent[2]

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
69478394866M7891
assay

≥98.5% (GC)

assay

≥97.0%

assay

≥98%

assay

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

reaction suitability

-

bp

130-132 °C (lit.)

bp

-

bp

130-132 °C (lit.)

bp

130-132 °C (lit.)

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

density

1.075 g/mL at 25 °C (lit.)

density

-

density

1.075 g/mL at 25 °C (lit.)

density

1.07 g/mL at 25 °C (lit.), 1.075 g/mL at 25 °C (lit.)


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pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Klasa składowania

3 - Flammable liquids

wgk

WGK 3

flash_point_f

77.0 °F - closed cup

flash_point_c

25 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Protokoły

Example displays how MSTFA/MSTFA-d9 derivatization of amphetamine provides valuable information in mass spectra and chromatograms using SLB-5ms GC column.

Produkty

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Development and validation of a fatty acid methyl esterification method, using methanolic HCl reagent, for FAME analysis by GC of vegetable oils and fats.

Powiązane treści


Hieng-Ming Ting et al.
Frontiers in plant science, 11, 257-257 (2020-03-27)
Glucosinolates are defense-related secondary metabolites found in Brassicaceae. When Brassicaceae come under attack, glucosinolates are hydrolyzed into different forms of glucosinolate hydrolysis products (GHPs). Among the GHPs, isothiocyanates are the most comprehensively characterized defensive compounds, whereas the functional study of
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Journal of Chromatography A, 115, 591-591 (1975)



Numer pozycji handlu globalnego

SKUNUMER GTIN
69479-25ML04061837684104
69479-1ML04061837684098
69479-10X1ML04061837684081
69479-5ML04061837684111

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the packaging of the product N-Methyl-N-(trimethylsilyl)trifluoroacetamide, code: 69479-10X1ML, bottle, ampoule, blister or other??

    1 answer
    1. The 1ML size is packaged in a 5mL amber glass vial with a Schwarz-type septum cap. The vials are then placed in a 10-place overpack box with dividers to protect each vial. Please see the image below of this cap type.

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