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Sigma-Aldrich

L-Cysteine hydrochloride monohydrate

tested according to Ph. Eur.

Synonim(y):

Cysteini hydrochloridum monohydricum

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About This Item

Wzór liniowy:
HSCH2CH(NH2)COOH · HCl · H2O
Numer CAS:
7048-04-6
Masa cząsteczkowa:
175.63
Beilstein:
5158059
Numer WE:
200-157-7
Numer MDL:
MFCD00065606
Kod UNSPSC:
12352209
eCl@ss:
32160406
Identyfikator substancji w PubChem:
329753438

agency

USP/NF
tested according to Ph. Eur.

Poziom jakości

100

Próba

98.5-101.0%

Postać

solid

mp

176 °C

rozpuszczalność

H2O: soluble 100 g/L at 25 °C

Zastosowanie

pharmaceutical (small molecule)

ciąg SMILES

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

Klucz InChI

QIJRTFXNRTXDIP-JIZZDEOASA-N

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Zastosowanie

L-Cysteine hydrochloride monohydrate was used in the synthesis of polycarbophil-cysteine conjugate.

Działania biochem./fizjol.

Cysteine is a non-essential, thiol-containing amino acid that has protective effects in normal tissues. It is converted to glutathione that decreases the effects of chemotherapeutic and radiation agents. This might restrict the effect of therapeutic agents used for cancer treatment.
NMDA glutamatergic receptor antagonist.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves

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Certyfikaty analizy (CoA)

Lot/Batch Number
BCBL3252V
BCBK6080V
BCBK4297V
BCBJ4111V
BCBH2069V

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

M K Marschütz et al.
Pharmaceutical research, 17(12), 1468-1474 (2001-04-17)
To develop an oral controlled release system for insulin. The polymer-inhibitor conjugates carboxymethylcellulose (CMC)-Bowman-Birk inhibitor and CMC-elastatinal were homogenized with polycarbophil-cysteine conjugate, insulin, and mannitol, compressed to 2 mg microtablets and enteric coated with a polymethacrylate. The protective effect of
Matthew Oser et al.
Journal of cell science, 123(Pt 21), 3662-3673 (2010-10-26)
Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells enriched in proteins that regulate actin polymerization. The on-off regulatory switch that initiates actin polymerization in invadopodia requires phosphorylation of tyrosine residues 421, 466, and 482 on cortactin. However, it is
J C Roberts
Amino acids, 8(2), 113-124 (1995-06-01)
The thiol-containing amino acid, cysteine, and its analogs are useful for a variety of protective applications, including protecting normal tissues against the unwanted side effects of cancer chemotherapeutic agents and radiation treatment. The protection can result from both direct action
Jiahua Li et al.
American journal of physiology. Cell physiology, 305(2), C190-C196 (2013-05-17)
Claudins constitute a family of tight junction transmembrane proteins whose first extracellular loop (ECL1) determines the paracellular permeability and ion selectivity in epithelia. There are two cysteines in the ECL1 that are conserved among all claudins. We hypothesized that these
Edward T Chouchani et al.
Nature medicine, 19(6), 753-759 (2013-05-28)
Oxidative damage from elevated production of reactive oxygen species (ROS) contributes to ischemia-reperfusion injury in myocardial infarction and stroke. The mechanism by which the increase in ROS occurs is not known, and it is unclear how this increase can be
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Produkty

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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