25107

Potassium citrate tribasic monohydrate

meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)

• Synonim(y): Citric acid tripotassium salt, Tripotassium citrate
• Wzór liniowy: HOC(COOK)(CH₂COOK)₂ · H₂O
• Numer CAS: 6100-05-6
• Masa cząsteczkowa: 324.41
• UNSPSC Code: 12352100
• NACRES: NA.21
• PubChem Substance ID: 57648111
• EC Number: 231-905-0
• Beilstein/REAXYS Number: 3924344
• MDL number: MFCD00150442

Właściwości

• Quality Segment: 200
• assay: 99-100.5% (calc with ref. to anhyd. subst.)
• form: powder or crystals
• quality: meets analytical specification of Ph. Eur., BP, FCC, E332
• impurities: ≤0.0005% heavy metals (as Pb), 4-6% water (Karl Fischer)
• loss: 3-6 loss on drying, 180°C
• pH: 7-9 (20 °C, 5%)
• mp: 275 °C (dec.) (lit.)
• solubility: glycerol: soluble 1 gm in 2.5 ml, water: soluble 1 gm in 0.65 ml, alcohol: insoluble
• anion traces: chloride (Cl^-): ≤30 mg/kg, oxalate (as oxalic acid): ≤100 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: As: ≤1 mg/kg, Cu: ≤10 mg/kg, Fe: ≤10 mg/kg, Hg: ≤1 mg/kg, Na: ≤3000 mg/kg, Pb: ≤1 mg/kg, Zn: ≤10 mg/kg
• suitability: in accordance for appearance of solution, passes test for reaction against H₂SO₄
• application(s): pharmaceutical (small molecule)
• SMILES string: O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3
• InChI key: PJAHUDTUZRZBKM-UHFFFAOYSA-K

Opis

Application

Potassium citrate tribasic monohydrate has been used for preparing citrate-supplemented water for feeding the Car5A, Car5B, and DKO breeding pairs of mice. Citrate supplementation enhances the perinatal death in mice.[1] It is a citrate-based salt used as a phase constituent for characterizing ionic-liquid-based aqueous biphasic systems (ABS) and as a buffering agent.

Biochem/physiol Actions

Potassium citrate tribasic monohydrate is the potassium salt of citric acid. It enhances the bone density hence used in the treatment of osteoporosis.[2] Additionally, it neutralizes the protein-induced metabolic acidosis.[3]

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)