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21980

Cardiogreen

suitable for microscopy

Synonim(y):

Foxgreen, IC Green, Indocyanine green

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Gabaryty przesyłkiSKUDostępnośćCena netto
100 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
1300,00 zł
500 mg
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5170,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C43H47N2NaO6S2
Numer CAS:
Masa cząsteczkowa:
774.96
UNSPSC Code:
12171500
NACRES:
MA.02
PubChem Substance ID:
EC Number:
222-751-5
Beilstein/REAXYS Number:
4115884
MDL number:

1300,00 zł


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form

powder

Quality Segment

technique(s)

titration: suitable

color

green to very dark green

solubility

water: 0.01 g/10 mL

ε (extinction coefficient)

≥115 at 386-396 nm in water, ≥2000 at 774-784 nm in water, ≥900 at 712-722 nm in water

suitability

suitable for microscopy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CC1(C)/C(=C\C=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccc4ccccc4c3C2(C)C)N(CCCCS([O-])(=O)=O)c5ccc6ccccc6c15

InChI

1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1

InChI key

MOFVSTNWEDAEEK-UHFFFAOYSA-M

General description

Cardiogreen is a dye used for microscopy. This dye has its maximum extinction at the same wavelength as reduced and oxygenated haemoglobin meet making it possible to record the oxygen saturation in blood. This dye has no side-effects.[1]

Application

Cardiogreen was injected in animals intravenously for dynamic optical imaging system to study the capability of capturing the in vivo biodistribution kinetics.[2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

A diagnostic aid in the determination of hepatic function
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1340009I2633B6756
technique(s)

titration: suitable

technique(s)

-

technique(s)

titration: suitable

technique(s)

-

suitability

suitable for microscopy

suitability

-

suitability

-

suitability

-

color

green to very dark green

color

-

color

green to very dark green

color

blue-green

form

powder

form

-

form

powder

form

powder

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

pharmaceutical (small molecule)

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

solubility

water: 0.01 g/10 mL

solubility

-

solubility

water: 0.01 g/mL

solubility

H2O: 1 mg/mL


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Elizabeth M C Hillman et al.
Nature photonics, 1(9), 526-530 (2008-11-01)
Optical molecular imaging in small animals harnesses the power of highly specific and biocompatible contrast agents for drug development and disease research1-7. However, the widespread adoption of in vivo optical imaging has been inhibited by its inability to clearly resolve
Determination of cardiac output with cardio green in a direct writing colorimeter.
B HYSING et al.
Scandinavian journal of clinical and laboratory investigation, 14, 430-434 (1962-01-01)
C.M. Leevy et al.
Probl. Liver Dis. (Review), 42-42 (1979)



Numer pozycji handlu globalnego

SKUNUMER GTIN
21980-100MG-F04061833488782
21980-500MG-F04061833488799

Questions

1–6 of 6 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  2. Can Product No. I2633, Cardiogreen, be used as a biological stain?

    1 answer
    1. Limited absorbance in the visible region practically precludes the use of Indocyanine Green as a biological stain. See: Sigma-Aldrich Handbook of Dyes, Stains, and Indicators, Green, F. ed., p. 407.

      Helpful?

  3. Does Cardiogreen dissolve equally well in saline and in water?

    1 answer
    1. Each lot is tested for solubility in hot water at 1 mg/mL. We have found that Sigma Product No. I2633 (which has the same CAS number as Product No. 21980) dissolves in water at 1 mg/mL without heating. Further dilute in saline to prepare an isotonic solution.

      Helpful?

  4. Has Cardiogreen been used for in vivo optical imaging studies?

    1 answer
    1. We do not subject this product to in vivo testing. However, one study documents the use of the product in a study with mice:For optical imaging, mice were injected intravenously with a mixture of 0.05 ml of 260 μM ICG (Cardiogreen) and 0.05 ml of 360 μM DTR (70,000 MW, Invitrogen) in saline (equivalent to 0.4 mg per kg or 7.4 μM initial concentration in blood).

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  5. How long can I store a solution of Cardiogreen after it has been prepared?

    1 answer
    1. Sigma-Aldrich recommends that solutions be prepared fresh and not stored. Solutions "are stable only for a few hours and cannot be kept overnight." See: Sigma-Aldrich Handbook of Dyes, Stains, and Indicators, Green, F. ed., p. 407.

      Helpful?

  6. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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