MAB379
Przeciwciało przeciwko receptorom glutaminianu 5, 6, 7, klon 4F5
ascites fluid, clone 4F5, Chemicon®
Synonim(y):
GluR5/6/7
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μL | Przewidywany termin wysyłki25 czerwca 2026zKuehne + Nagel Sp. z o.o. | 2450,00 zł |
Informacje o tej pozycji
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
4F5, monoclonal
species reactivity
rat, human, monkey
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, radioimmunoassay: suitable
isotype
IgM
NCBI accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRIK1(2897)
Immunogen
Application
ELISA
RIA
Optymalne rozcieńczenia robocze muszą być określone przez użytkownika końcowego.
Neuroscience
Neurotransmitters & Receptors
Biochem/physiol Actions
Physical form
Preparation Note
Legal Information
Disclaimer
1 of 1
Ta pozycja | |||
|---|---|---|---|
| clone 4F5, monoclonal | clone 3A11, monoclonal | clone polyclonal | clone 3B3, monoclonal |
| antibody form ascites fluid | antibody form purified immunoglobulin | antibody form affinity purified immunoglobulin | antibody form purified antibody |
| Gene Information human ... GRIK1(2897) | Gene Information human ... GRIA2(2891) | Gene Information human ... GRIA1(2890) | Gene Information human ... GRIA3(2892) |
| conjugate unconjugated | conjugate unconjugated | conjugate - | conjugate unconjugated |
| biological source mouse | biological source mouse | biological source rabbit | biological source mouse |
| species reactivity rat, human, monkey | species reactivity monkey, human, rat | species reactivity rat | species reactivity monkey, mouse, human |
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Klasa składowania
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Powiązane treści
Glutamate is an excitatory neurotransmitter found in the synaptic vesicles of glutamatergic synapses. The post-synaptic neurons in these synapses contain ionotropic and metabotropic glutamate receptors. Glutamate binds to AMPA (α-amino-3-hydroxy-5- methylisoxazole-4-propionic acid) subtype glutamate receptors, leading to sodium influx into the post-synaptic cell and resulting in neuronal excitability and synaptic transmission. The NMDA (N-methyl-d-aspartate) subtype glutamate receptors, on the other hand, regulate synaptic plasticity, and can influence learning and memory. The metabotropic g-protein coupled mGluRs modulate downstream calcium signaling pathways and indirectly influence the synapse’s excitability. The synaptic architecture includes intracellular scaffolding proteins (PSD-95, GRIP), intercellular cell adhesion molecules (NCAMs, N-Cadherins), and a variety of signaling proteins (CaMKII/PKA, PP1/PP2B). Processes critical for synaptic transmission and plasticity are influenced by these molecules and their interactions. When the function of these molecules is disrupted, it leads to synaptic dysfunction and degeneration, and can contribute to dementia as seen in Alzheimer’s disease.
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MAB379 | 04053252464515 |