MAB396
Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11
clone 3A11, Chemicon®, from mouse
Synonim(y):
GluR2/4
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
3A11, monoclonal
reaktywność gatunkowa
monkey, human, rat
producent / nazwa handlowa
Chemicon®
metody
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable
western blot: suitable
izotyp
IgG2a
numer dostępu NCBI
Warunki transportu
dry ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... GRIA2(2891)
rat ... Gria2(29627)
rhesus monkey ... Gria2(574344)
Specyficzność
Glutamate Receptor 2 (GluR2) by Western blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.
Immunogen
Recombinant fusion protein TrpE-GluR2
Zastosowanie
Detect Glutamate Receptor 2 & 4 using this Anti-Glutamate Receptor 2 & 4 Antibody, clone 3A11 validated for use in ELISA, IC, IH, IP, RIA & WB.
Immunohistochemistry on 4% paraformaldehyde fixed
tissue: 1:500-1,000
Immunocytochemistry
ELISA
RIA
Optimal working dilutions must be determined by end user.
tissue: 1:500-1,000
Immunocytochemistry
ELISA
RIA
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Postać fizyczna
Format: Purified
Purified immunoglobulin. Liquid in PBS, no preservative.
Przechowywanie i stabilność
Maintain at -20°C in undiluted aliquots for up 12 months. Avoid repeated freeze/thaw cycles.
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Sheng Chen et al.
Journal of neuroscience research, 81(4), 522-529 (2005-06-11)
Lipid rafts are specialized plasma membrane microdomains enriched in cholesterol and sphingolipids that serve as major assembly and sorting platforms for signal transduction complexes. Constitutively expressed heat shock proteins Hsp90, Hsc70, Hsp60, and Hsp40 and a range of neurotransmitter receptors
Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.
Dannis G van Vuurden et al.
PloS one, 4(6), e5953-e5953 (2009-06-19)
Glioblastoma multiforme (GBM) cells secrete large amounts of glutamate that can trigger AMPA-type glutamate receptors (AMPARs). This commonly results in Na(+) and Ca(2+)-permeability and thereby in excitotoxic cell death of the surrounding neurons. Here we investigated how the GBM cells
Shoko Shimizu et al.
Glia, 62(5), 709-724 (2014-02-01)
Recent studies have shown changes in myelin genes and alterations in white matter structure in a wide range of psychiatric disorders. Here we report that DBZ, a central nervous system (CNS)-specific member of the DISC1 interactome, positively regulates the oligodendrocyte
Ester Orav et al.
Molecular neurobiology, 56(11), 7473-7489 (2019-05-03)
Kainate type ionotropic glutamate receptors (KARs) are expressed in hippocampal interneurons and regulate interneuron excitability and GABAergic transmission. Neuropilin tolloid-like proteins (NETO1 and NETO2) act as KAR auxiliary subunits; however, their significance for various functions of KARs in GABAergic interneurons
R Fabian-Fine et al.
The European journal of neuroscience, 12(10), 3687-3700 (2000-10-13)
Organotypic slice cultures of rat hippocampus are widely used as experimental preparations for the study of synaptic plasticity, but their degree of correspondence with intact brain is not fully known. Here, using postembedding immunogold labelling, we describe the ultrastructural distribution
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