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MAB2053

Anti-Disialoganglioside GD3 Antibody, clone MB3.6

clone MB3.6, Chemicon®, from mouse

Synonim(y):

GD3 Antibody

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Gabaryty przesyłkiSKUDostępnośćCena netto
100 μg

Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o.

1870,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
MB3.6, monoclonal
Species reactivity:
human
Application:
FACS, IF, IHC
Citations:
6

1870,00 zł

Dostępne do wysyłki DZISIAJSzczegóły

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Pozwól nam pomóc

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

MB3.6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable

isotype

IgG3

shipped in

wet ice

target post-translational modification

unmodified

Immunogen

FM9 melanoma cells

Application

Anti-Disialoganglioside GD3 Antibody, clone MB3.6 is an antibody against Disialoganglioside GD3 for use in FC, IF, IH.
Immunohistochemistry (frozen tissue sections)

Immunofluorescence of cells in culture

Flow cytometry: 1-2 μg per 10E6 cells

Lysis of GD3 positive (melanoma) cells in presence of complement (Cheresh et al., 1985).

Induction of antibody dependent cellular cyotoxicity (ADCC) {Ortaldo JR et al 1987 J Immunol 138(10):3566-3572.

TLC analysis: Sjoberg, ER (1995) J. Biol. Chem. 270(7):2921-2930.{http://www.jbc.org/cgi/content/full/270/7/2921}





Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts specifically with human GD3 ganglioside (Cheresh et al., 1984). No cross-reactivity with other gangliosides purified from neuroblastoma or melanoma cells.

Physical form

Format: Purified
Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% NaN3.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Anti-Disialoganglioside GD3 Antibody, clone MB3.6 clone MB3.6, Chemicon®, from mouse

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Anti-Nuclei Antibody, clone 3E1.3 clone 3E1.3, Chemicon®, from mouse

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Anti-Nuclei Antibody, clone 3E1.3

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

species reactivity

human

species reactivity

human, chicken

species reactivity

human

species reactivity

human

clone

MB3.6, monoclonal

clone

P1F6, monoclonal

clone

15E8, monoclonal

clone

3E1.3, monoclonal

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified antibody

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, immunofluorescence: suitable

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable

technique(s)

flow cytometry: suitable

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable

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Klasa składowania

12 - Non Combustible Liquids

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Suzanne M Birks et al.
Neuro-oncology, 13(9), 950-960 (2011-08-03)
The expression of ganglioside GD3, which plays crucial roles in normal brain development, decreases in adults but is upregulated in neoplastic cells, where it regulates tumor invasion and survival. Normally a buildup of GD3 induces apoptosis, but this does not
Seth H Pincus et al.
Vaccine, 30(32), 4849-4858 (2012-05-29)
Group B streptococcus (GBS) is a major cause of neonatal sepsis and meningitis. Despite aggressive campaigns using antenatal prophylactic antibiotic therapy, infections continue. Developing an effective maternal vaccine is a public health priority. Antibody (Ab) to the capsular polysaccharide (CPS)
Rebecca L Mather et al.
Scientific reports, 9(1), 8609-8609 (2019-06-15)
Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups
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Numer pozycji handlu globalnego

SKUNUMER GTIN
MAB205304053252728174

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