CBL517
Anti-CD28 Antibody, clone 15E8
clone 15E8, Chemicon®, from mouse
Synonim(y):
Tp44
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μg | Przewidywany termin wysyłki19 maja 2026zKuehne + Nagel Sp. z o.o. | 1680,00 zł |
Informacje o tej pozycji
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
15E8, monoclonal
Application:
FACS
Citations:
3
1680,00 zł
Przewidywany termin wysyłki19 maja 2026Szczegóły
Rekombinowane, niezawierające konserwantów przeciwciało jest dostępne dla Twojego celu. Wypróbuj ZRB1298
Pomoc techniczna
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Pozwól nam pomócbiological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
15E8, monoclonal
species reactivity
human
should not react with
canine
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CD28(940)
Immunogen
Human T lymphocytes
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
This Anti-CD28 Antibody, clone 15E8 is validated for use in FC, FUNC for the detection of CD28.
To study the role of CD28 in T cell proliferation. The antibody will induce the proliferation of resting T lymphocytes.
This antibody will act in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4 + cell counts
Optimal working dilutions must be determined by the end user.
This antibody will act in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4 + cell counts
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
This antibody reacts with the 44 kDa antigen found on a sub-population of T cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T cell precursors. The antibody does not react with B cells, granulocytes or monocytes. The ligand for CD28 is CD80 (B7) which is found on activated B cells suggesting a role for CD28 in T and B cell interaction
FUSION PARTNER: SP2/0
FUSION PARTNER: SP2/0
Physical form
Format: Purified
Please see lot specific datasheet for product formulation. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Preparation Note
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL517P
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja | |||
|---|---|---|---|
| antibody form purified antibody | antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form purified antibody |
| clone 15E8, monoclonal | clone polyclonal | clone CD28.2, monoclonal | clone CD28.2, monoclonal |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate Allophycocyanin conjugate |
| species reactivity human | species reactivity mouse, human, rat | species reactivity nonhuman primates, human | species reactivity human |
| Gene Information human ... CD28(940) | Gene Information human ... CD28(940) | Gene Information human ... CD28(940) | Gene Information human ... CD28(940) |
| biological source mouse | biological source rabbit | biological source mouse | biological source mouse |
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Klasa składowania
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Eduardo Huarte et al.
Blood, 112(4), 1259-1268 (2008-06-14)
Robust T-cell responses without autoimmunity are only possible through a fine balance between activating and inhibitory signals. We have identified a novel modulator of T-cell expansion named proliferation-induced lymphocyte-associated receptor (PILAR). Surface PILAR is markedly up-regulated on CD4 and, to
D Rushworth et al.
Gene therapy, 23(2), 119-128 (2015-08-15)
Antithymidylates (AThy) constitute a class of drugs used in the treatment of cancers such as lung, colon, breast and pancreas. These drugs inhibit DNA synthesis by targeting the enzymes dihydrofolate reductase (DHFR) and/or thymidylate synthase (TYMS). AThys effectively inhibit cancer
Maria C Lebre et al.
Journal of leukocyte biology, 101(3), 775-783 (2016-10-14)
Bone and cartilage destruction is one of the key manifestations of rheumatoid arthritis (RA). Although the role of T helper (Th)17 cells in these processes is clear, the role of IL-21-producing cells T cells has been neglected. We sought to
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| CBL517 | 04053252589904 |