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MAB1904

Sigma-Aldrich

Anti-Laminin-1 A&B chains Antibody

CHEMICON®, rat monoclonal, AL-2

Synonim(y):

laminin alpha1, laminin beta1

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Wybierz wielkość

100 μG
1890,00 zł

1890,00 zł


Przewidywany termin wysyłki21 marca 2025Szczegóły


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Wybierz wielkość

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100 μG
1890,00 zł

About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

1890,00 zł


Przewidywany termin wysyłki21 marca 2025Szczegóły


Poproś o zamówienie zbiorcze

Nazwa produktu

Anti-Laminin-1 A&B chains Antibody, cross region, clone AL-2, clone AL-2, Chemicon®, from rat

pochodzenie biologiczne

rat

Poziom jakości

forma przeciwciała

purified antibody

rodzaj przeciwciała

primary antibodies

klon

AL-2, monoclonal

reaktywność gatunkowa

mouse

producent / nazwa handlowa

Chemicon®

metody

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

izotyp

IgG1κ

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

mouse ... Lama1(16772)

Opis ogólny

Laminins are secreted glycoproteins incorporated into cell-associated extracellular matrices and an integral part of the structural scaffolding in most animal tissues. The laminin protein is made up of three polypeptide chains; α, β and γ, accounting for its flexibility in connecting various molecules. When originally characterized, laminin-1 clone AL-2 reacted with Engelbreth-Holm-Swarm (EHS) mouse laminin A & B chains on the long arm near the cross region, (Skubitz, 1987). More recently, investigations, (Schèele, 2006) have shown that the clone binds laminin β1 under reducing conditions as well as native ELISAs and that the affinity is increased by the presence of the laminin α1 chain. Thus there is significant laminin β1 reactivity with clone AL-2.

Specyficzność

Other species have not been tested.
Reacts with EHS mouse laminin A & B chains on the long arm near the cross region.

Immunogen

Epitope: Near cross region
Laminin isolated from EHS mouse sarcoma.

Zastosowanie

Detect Laminin-1 A&B chains using this Anti-Laminin-1 A&B chains Antibody, cross region, clone AL-2 validated for use in ELISA, IF, IH(P), IP & WB.
Immunofluorescence:
An independent laboratory (Schèele, S., 2006) has verified anti-laminin clone AL-2 to work using immunofluorescence techniques on mouse muscle tissue, including both transgenic and wild-type tissues.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

Jakość

Evaluated on a representative lot by Western blot on purified mouse laminin-1.

Opis wartości docelowych

~200 kDa

Postać fizyczna

Format: Purified
Protein G Purified
Purified in 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% NaN3.

Przechowywanie i stabilność

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

George S Karagiannis et al.
Molecular oncology, 8(2), 178-195 (2013-11-26)
It has been suggested that cancer-associated fibroblasts (CAFs) positioned at the desmoplastic areas of various types of cancer are capable of executing a migratory program, characterized by accelerated motility and collective configuration. Since CAFs are reprogrammed derivatives of normal progenitors
H Kurata et al.
The Journal of allergy and clinical immunology, 103(5 Pt 2), S471-S484 (1999-05-18)
Adenoviruses have several specific features useful for gene therapy. They infect various lineages of cells irrespective of cell cycle status. However, the exact mechanism of their infection and in vivo kinetics as a gene expression vector have not been elucidated.
Ghaidaa Kashgari et al.
Developmental cell, 52(6), 764-778 (2020-02-29)
The fusion of digits or toes, syndactyly, can be part of complex syndromes, including van der Woude syndrome. A subset of van der Woude cases is caused by dominant-negative mutations in the epithelial transcription factor Grainyhead like-3 (GRHL3), and Grhl3-/-mice
Jangwook P Jung et al.
Biomacromolecules, 14(9), 3102-3111 (2013-07-24)
Limiting the precise study of the biochemical impact of whole molecule extracellular matrix (ECM) proteins on stem cell differentiation is the lack of 3D in vitro models that can accommodate many different types of ECM. Here we sought to generate
Raven Diacou et al.
Cell reports, 25(9), 2510-2523 (2018-11-30)
Gene regulation of multipotent neuroretinal progenitors is partially understood. Through characterizing Six3 and Six6 double knockout retinas (DKOs), we demonstrate Six3 and Six6 are jointly required for the maintenance of multipotent neuroretinal progenitors. Phenotypes in DKOs were not found in

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