DX1726

N,N-Dimethylformamide

OmniSolv^®

• Synonim(y): Formic Acid Dimethylamide, DMF, DMF, NSC 5356
• Wzór liniowy: HCON(CH₃)₂
• Numer CAS: 68-12-2
• Masa cząsteczkowa: 73.09
• EC Index Number: 200-679-5
• UNSPSC Code: 12352111
• Beilstein/REAXYS Number: 605365
• MDL number: MFCD00003284
• eCl@ss: 39031202
• Assay: ≥99.9% (GC)
• Technique(s): HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable
• Bp: 153 °C (lit.)
• Vapor pressure: 2.7 mmHg ( 20 °C)

Właściwości

• Quality Segment: 100
• vapor density: 2.5 (vs air)
• vapor pressure: 2.7 mmHg ( 20 °C)
• product line: OmniSolv^®
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 833 °F
• shelf life: 24 mo.
• expl. lim.: 15.2 %
• technique(s): HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable
• impurities: <0.05% Water
• evapn. residue: <5 ppm
• color: APHA: 10
• refractive index: n20/D 1.430 (lit.)
• pH: 7 (20 °C, 200 g/L in H₂O)
• bp: 153 °C (lit.)
• mp: −61 °C (lit.)
• transition temp: flash point 57.5 °C
• density: 0.944 g/mL (lit.)
• UV cutoff: ≤268 nm
• UV absorption: λ: 268 nm A_max: ≤1.00, λ: 270 nm A_max: ≤0.75, λ: 275 nm A_max: ≤0.30, λ: 295 nm A_max: ≤0.07, λ: 310 nm A_max: ≤0.03, λ: 340 nm A_max: ≤0.01
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• InChI key: ZMXDDKWLCZADIW-UHFFFAOYSA-N

Opis

General description

N,N - Dimethylformamide (DMF) is a highly effective polar aprotic solvent for a wide range of compounds. This is due to its ability to interact effectively with different compounds. DMF can function as both an electrophilic and nucleophilic agent, and it can provide various key intermediates that mediate chemical reactions.

Application

OmniSolv^®

Solvent for many hydrophobic organic compounds.

N,N-Dimethylformamide (DMF) is used

• As a solvent in the Wittig reaction for synthesizing α-hydroxy amides.
• In the preparation of the Vilsmeier reagent when treated with phosphorus oxychloride or other acid chlorides, which is utilized for formylating, halogenating, and dehydroxylating reactions.
• As a solvent in the synthesis of alkyl halides from alcohols.
• As a co-solvent to examine the relationship between medium polarity and drug solubility.

Packaging

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!

is packaged in 1L amber glass bottle

is packaged in 4L amber glass bottle

is packaged in 4L polycoated glass bottle

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Assay (GC): 99.9% min
Color (APHA): 10 max
Evaporation residue: 5ppm max
Expiration date: 24 months
Filtered through 0.2 m filter: To pass test
Form: Clear liquid
Infrared Spectrum: Conforms to standard
Titrable acid: eq/g
Titrable base: eq/g
UV Abs. at 268 nm: 1.00AU max
UV Abs. at 270 nm: 0.75AU max
UV Abs. at 275 nm: 0.30AU max
UV Abs. at 295 nm: 0.07AU max
UV Abs. at 310 nm: 0.03AU max
UV Abs. at 340 nm: 0.01AU max
UV Cut-off: 268nm max
Water (H₂O): 0.05% max

Legal Information

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H226,H312 + H332,H319,H360D
• pcodes: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Klasa składowania: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 135.5 °F - closed cup
• flash_point_c: 57.5 °C - closed cup