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Informacje o tej pozycji
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... KATNAL1(84056)
General description
Katanin-like 1 (KL1) is a mitotic regulator that is very closely related to katanin. KL1 is thought to be involved in microtubule severing because increased expression of KL1 leads to total disassembly of microtubules. KL1 is seen to localize to the spindle poles during mitosis, not to the centrosome.
~55 kDa observed. Uncharacterized bands at ~210, 150, 63, and 45 may be observed in some lysates.
Immunogen
KLH-conjugated linear peptide corresponding to human KL1.
Application
Anti-Katanin-like 1 (KL1) Antibody is a Rabbit Polyclonal Antibody for detection of Katanin-like 1 (KL1) also known as Katanin p60 subunit A-like 1 & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Cell Cycle, DNA Replication & Repair
Western Blot Analysis: A 1:1.000 dilution of this antibody detected KL1 on 10 µg of U2OS cell lysate.
Immunocytochemistry: A representative lot of this antibody was used for IC by an independent laboratory (Sonbuchner, T.M., et al. (2010). Cell Cycle. 9(12):2403-2411).
Immunocytochemistry: A representative lot of this antibody was used for IC by an independent laboratory (Sonbuchner, T.M., et al. (2010). Cell Cycle. 9(12):2403-2411).
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
HeLa cell lysate
HeLa cell lysate
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: A 1:1.000 dilution of this antibody detected KL1 on 10 µg of HeLa cell lysate.
Western Blot Analysis: A 1:1.000 dilution of this antibody detected KL1 on 10 µg of HeLa cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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