AB9882
Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody
Chemicon®, from rabbit
Synonim(y):
HIP1R
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μL | Przewidywana wysyłka DZISIAJzKuehne + Nagel Sp. z o.o. | 1930,00 zł |
Informacje o tej pozycji
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, WB
Citations:
6
Pomoc techniczna
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Pozwól nam pomócbiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, rat, human
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... HIP1R(9026)
General description
Huntingtin-Interacting protein-1 related (HIP1R) is an actin-binding protein that is considered an element of the clathrin-coated pits and vesicles and polymerizes actin. HIP1R is essential for normal actin organization and endocytosis. HIP1R is equipped with a epsin N-terminal homology domain which allows it to bind 3-phosphorylated inositol lipids, which allows HIP1R to function as a tyrosine kinase stabilizing receptor and plays a role in overall cell growth and survival.
~116 kDa
Immunogen
Synthetic peptide
Application
Detect Huntingtin-Interacting Protein 1 Related (HIP1R) using this Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody validated for use in WB & IC.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Synapse & Synaptic Biology
Neurodegenerative Diseases
Synapse & Synaptic Biology
Western Blot: a 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.A 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.
Immunocytochemistry: a previous lot of this antibody was used by an independent laboratory for IC of human cells. (Poupon, V., et al. (2008). PNAS. 105(1): 168-173.)
Optimal working dilutions must be determined by end user.
Immunocytochemistry: a previous lot of this antibody was used by an independent laboratory for IC of human cells. (Poupon, V., et al. (2008). PNAS. 105(1): 168-173.)
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Huntingtin-interacting protein 1 related (HIP1R). By Western blot the antibody recognizes a band at ~116 kDa on P2 microsomal fraction from embryonic rat brain.
Physical form
Format: Purified
Liquid
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja | |||
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| antibody form purified antibody | antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form purified antibody |
| biological source rabbit | biological source mouse | biological source rabbit | biological source rabbit |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| clone polyclonal | clone polyclonal | clone polyclonal | clone polyclonal |
| Gene Information human ... HIP1R(9026) | Gene Information human ... HIP1R(9026) | Gene Information human ... HIP1(3092) | Gene Information human ... WASH1(100287171) |
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Klasa składowania
10 - Combustible liquids
wgk
WGK 1
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
M A Rice et al.
Oncogene, 35(36), 4752-4761 (2016-02-24)
Deregulation of microRNAs (miRs) contributes to progression and metastasis of prostate and other cancers. miR-23b and -27b, encoded in the same miR cluster (miR-23b/-27b), are downregulated in human metastatic prostate cancer compared with primary tumors and benign tissue. Expression of
Qian Yang et al.
Frontiers in molecular neuroscience, 11, 447-447 (2018-12-24)
Huntington-interacting protein 1-related protein (HIP1R) was identified on the basis of its structural homology with HIP1. Based on its domain structure, HIP1R is a putative endocytosis-related protein. Our previous study had shown that knockdown of HIP1R induces a dramatic decrease
Mian Cao et al.
Neuron, 93(4), 882-896 (2017-02-24)
Synaptojanin 1 (SJ1) is a major presynaptic phosphatase that couples synaptic vesicle endocytosis to the dephosphorylation of PI(4,5)P2, a reaction needed for the shedding of endocytic factors from their membranes. While the role of SJ1's 5-phosphatase module in this process
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| AB9882 | 04053252731433 |