AB4350

Anti-PRDM14 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): PR domain zinc finger protein 14, PR domain-containing protein 14
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 3

Właściwości

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, mouse, human
• technique(s): western blot: suitable
• NCBI accession no.: NP_078780
• UniProt accession no.: Q9GZV8
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... PRDM14(63978)

Opis

General description

PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation.

~62 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14.

Application

This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14.

Biochem/physiol Actions

This antibody recognizes the N-terminus of PRDM14.

Analysis Note

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable