AB3096
Anti-Orexin Antibody, Prepro
Chemicon®, from rabbit
Synonim(y):
Anti-NRCLP1, Anti-OX, Anti-PPOX
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 50 μg | Przewidywany termin wysyłki13 kwietnia 2026zKuehne + Nagel Sp. z o.o. | 2450,00 zł |
Informacje o tej pozycji
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
18
Pomoc techniczna
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Pozwól nam pomócbiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PPOX(5498)
Immunogen
A 17 mer peptide (designated PPOXA11-A) mapping near the C-terminus of mouse prepro-Orexin.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
CNS Control of Metabolism
Circadian Rhythm & Sleep
CNS Control of Metabolism
Circadian Rhythm & Sleep
Western blot: 1-10 μg/mL using Chemiluminescence technique
ELISA: 1:10,000 - 100,000
Immunohistochemistry: 2-20 μg/mL.
Optimal working dilutions must be determined by end user.
ELISA: 1:10,000 - 100,000
Immunohistochemistry: 2-20 μg/mL.
Optimal working dilutions must be determined by end user.
Anti-Orexin Antibody, Prepro is an antibody against Orexin for use in ELISA, IH & WB.
Biochem/physiol Actions
Mouse Prepro-Orexin. Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (Sakurai et al. 1998). Orexin-A and Orexin-B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is an 130 aa peptide with a putative 33 aa secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis (Sakurai et al. 1998). These neuropeptides bind and activate two closely related Orexin receptors--G protein coupled receptors (GPCRs) OX1R and OX2R.
Physical form
Liquid in PBS with 0.1% BSA.
Preparation Note
Can be refrigerated at 2-8°C in undiluted aliquots for short term use. Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja | |||
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| biological source rabbit | biological source rabbit | biological source chicken | biological source mouse |
| antibody form affinity purified immunoglobulin | antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| Gene Information human ... PPOX(5498) | Gene Information human ... PPOX(5498) | Gene Information human ... PPOX(5498) | Gene Information human ... PPOX(5498) |
| species reactivity mouse, human, rat | species reactivity bovine, mouse, pig, rat, canine | species reactivity rat, human, mouse | species reactivity human |
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Powiązane treści
E Schéle et al.
Journal of neuroendocrinology, 24(6), 930-943 (2012-02-03)
Interleukin (IL)-6 deficient mice develop mature-onset obesity. Furthermore, i.c.v. administration of IL-6 increases energy expenditure, suggesting that IL-6 centrally regulates energy homeostasis. To investigate whether it would be possible for IL-6 to directly influence the energy homeostasis via hypothalamic regulation
Luigi Michele Pavone et al.
Anatomical record (Hoboken, N.J. : 2007), 292(2), 202-206 (2008-12-18)
The hypothalamic peptide orexin A (oxA) binds specifically the G-protein-coupled orexin receptor 1 (ox1R). It is involved in many physiological functions including the regulation of food intake, sleep-wake cycle, arterial blood pressure, heart rate, and sexual behavior. The localization of
Finizia Russo et al.
Anatomical record (Hoboken, N.J. : 2007), 291(2), 169-174 (2008-01-24)
Orexin A (oxA) and orexin B are recently discovered peptides derived from the proteolytic cleavage of the common precursor prepro-orexin. They bind two G protein-coupled receptors, defined orexin 1 (ox1R) and orexin 2 receptor. Both peptides are highly expressed in
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| AB3096 | 04053252369124 |