If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
5.43899
NMP
for liquid chromatography LiChrosolv®
Synonim(y):
1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 1 L | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 801,00 zł | |
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 920,00 zł | ||
| 2.5 L | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1730,00 zł |
Informacje o tej pozycji
801,00 zł
Nazwa produktu
1-Methyl-2-pyrrolidone, for liquid chromatography LiChrosolv®
vapor pressure
0.32 hPa ( 20 °C)
Quality Level
description
isocratic
product line
LiChrosolv®
assay
≥99.5% (GC)
form
liquid
autoignition temp.
245 °C
expl. lim.
1.3-9.5 % (v/v)
technique(s)
HPLC: suitable
impurities
≤0.05% Water
transmittance
300 nm, ≥50%, 325 nm, ≥90%, 350 nm, ≥97%, 400 nm, ≥99%
pH
8.5-10.0 (20 °C, 100 g/L in H2O)
bp
202 °C/1013 hPa
mp
-24 °C
transition temp
flash point 91 °C
solubility
1000 g/L
density
1.03 g/cm3 at 20 °C
storage temp.
2-30°C
SMILES string
N1(CCCC1=O)C
InChI
1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
InChI key
SECXISVLQFMRJM-UHFFFAOYSA-N
Application
- Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine: This study utilizes 1-Methyl-2-pyrrolidone (NMP) as a high-purity solvent in the formulation of a transdermal bioadhesive system, enhancing the solubility and delivery of antimalarial drugs. The application highlights NMP′s role in pharmaceutical formulations, particularly in improving drug efficacy and patient compliance (Volpe-Zanutto et al., 2021).
Analysis Note
Water: ≤ 0.05 %
Transmission (at 300 nm): ≥ 50 %
Transmission (at 325 nm): ≥ 90 %
Transmission (at 350 nm): ≥ 97 %
Transmission (at 400 nm): ≥ 99 %
Other Notes
Legal Information
1 of 1
Ta pozycja | |||
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| technique(s) HPLC: suitable | technique(s) GC-HS: suitable | technique(s) - | technique(s) - |
| assay ≥99.5% (GC) | assay ≥99.8% (GC) | assay ≥99.0% | assay 99% |
| solubility 1000 g/L | solubility 1000 g/L | solubility acetone: miscible(lit.), alcohol: miscible(lit.), benzene: miscible(lit.), chloroform: miscible(lit.), ethyl acetate: miscible(lit.), water: miscible(lit.) | solubility - |
| form liquid | form liquid | form liquid | form liquid |
| impurities ≤0.05% Water | impurities - | impurities ≤0.01% Free amines (as CH3NH2), ≤0.05% water | impurities ≤0.1% water (Karl Fischer) |
signalword
Danger
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Klasa składowania
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
195.8 °F - Pensky-Martens closed cup
flash_point_c
91 °C - Pensky-Martens closed cup
Wykazy regulacyjne
Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.
872-50-4
872-50-4
Certyfikaty analizy (CoA)
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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