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Merck

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443300

MCI-186

A free radical scavenger and antioxidant that reduces post-ischemic brain injury.

Synonim(y):

MCI-186, 3-Methyl-1-phenyl-2-pyrazolin-5-one, PMP, Edaravone

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Gabaryty przesyłkiSKUDostępnośćCena netto
500 mg
Sprawdź dostępność w koszyku
458,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C10H10N2O
Numer CAS:
Masa cząsteczkowa:
174.20
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light

458,00 zł


Sprawdź dostępność w koszyku

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Quality Segment

description

Merck USA index - 14, 6713

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

cream

solubility

DMSO: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key

QELUYTUMUWHWMC-UHFFFAOYSA-N

General description

A free radical scavenger and antioxidant that reduces post-ischemic brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.

Biochem/physiol Actions

Cell permeable: no
Primary Target
A free radical scavenger and antioxidant
Product does not compete with ATP.
Reversible: no
Target IC50: 15 µM inhibiting iron-dependent peroxidation in rat brain homogenates

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Katare, R. G., et al. 2003. Am. J. Physiol.285, H2171.
Kawai, H., et al. 1997. J. Pharmacol. Exp. Ther. 281, 921.
Yamamoto, Y., et al. 1996. Redox. Report 2, 333.
Watanabe, T., et al. 1994. J. Pharmacol. Exp. Ther. 268, 1597.
Nishi, H., et al. 1989. Stroke 20, 1236.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)
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Ta pozycja
373402324761438194
form

solid

form

solid

form

solid

form

powder

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, desiccated, protect from light

storage condition

OK to freeze, desiccated (hygroscopic), protect from light


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Klasa składowania

11 - Combustible Solids

wgk

WGK 1



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Numer pozycji handlu globalnego

SKUNUMER GTIN
443300-500MG04055977205350

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