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407137

D-myo-Inositol 1,4,5-Trisphosphate, trisodium salt

≥95% (TLC), solid, second messenger involved in Ca2+ mobilization, Calbiochem®

Synonim(y):

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, D-Ins(1,4,5)P3, 3Na

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Gabaryty przesyłkiSKUDostępnośćCena netto
1 mg
Sprawdź dostępność w koszyku
693,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C6H12O15P3 · 3Na
Numer CAS:
108340-81-4
Masa cząsteczkowa:
486.04
MDL number:
MFCD00055051
UNSPSC Code:
12352211
NACRES:
NA.77
Assay:
≥95% (TLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, desiccated (hygroscopic)

693,00 zł

Sprawdź dostępność w koszyku
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Nazwa produktu

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt, Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt.

Quality Level

100

assay

≥95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[P](=O)([O-])([O-])O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)O[P](=O)([O-])[O-])O)O)O[P](=O)([O-])[O-]

InChI

1S/C6H15O15P3.6Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;;;;/q;6*+1/p-6/t1-,2+,3+,4-,5-,6-;;;;;;/m1....../s1

InChI key

MLMBGBMAFNSCOW-PPKFVSOLSA-H

General description

Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).
Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt (Cat. No. 407123).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Mobilization of Ca2+ from intracellular stores.
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)
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Ta pozycja
I9766407125524644
D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt Sodium salt of D-Ins(1,4,5)P3 that has similar biological properties as the lithium salt.

Sigma-Aldrich

407137

D-myo-Inositol 1,4,5-Trisphosphate, Trisodium Salt

D-myo-Inositol 1,4,5-tris-phosphate trisodium salt ≥95% (by 1H NMR and TLC)

Sigma-Aldrich

I9766

D-myo-Inositol 1,4,5-tris-phosphate trisodium salt

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays Major phosphorus compound in plants that chelates with a variety of di- and trivalent cations.

Sigma-Aldrich

407125

D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate, Dodecasodium Salt, Zea mays

L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain A component of membrane-bound receptors in association with phospholipase C (PLC).

Sigma-Aldrich

524644

L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain

assay

≥95% (TLC)

assay

≥95% (by 1H NMR and TLC)

assay

≥85% (HPLC)

assay

≥98% (TLC)

form

solid

form

powder

form

solid

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

-

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Ka-Chun Mok et al.
Clinical and translational medicine, 11(11), e578-e578 (2021-11-30)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are members of the voltage-gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel-blocker, is FDA-approved for clinical use as a heart rate-reducing agent.
Jone Paesmans et al.
eLife, 9 (2020-12-23)
Synaptojanin1 (Synj1) is a phosphoinositide phosphatase, important in clathrin uncoating during endocytosis of presynaptic vesicles. It was identified as a potential drug target for Alzheimer's disease, Down syndrome, and TBC1D24-associated epilepsy, while also loss-of-function mutations in Synj1 are associated with

Numer pozycji handlu globalnego

SKUNUMER GTIN
407137-1MG04055977188592

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