341482
Ferritin, Human Liver
Ferritin, Human Liver, CAS 9007-73-2, is a native, sterile-filtered ferritin that is suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling.
Synonim(y):
Ferritin, Human Liver
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About This Item
Polecane produkty
pochodzenie biologiczne
human
Poziom jakości
Próba
≥95% (SDS-PAGE)
Postać
liquid
producent / nazwa handlowa
Calbiochem®
warunki przechowywania
do not freeze
metody
enzyme immunoassay: suitable
zanieczyszczenia
Antibodies to HIV1, HIV2, Hepatitis B, Hepatitis C, tested negative (by certified tests)
rozpuszczalność
water: soluble
przydatność
suitable for immunoassay
numer dostępu Protein ID
Warunki transportu
wet ice
temp. przechowywania
2-8°C
informacje o genach
human ... FTH1(2495) , FTL(2512)
Opis ogólny
Research area: Cell signaling
Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain. Native ferritin from human liver. Sterile-filtered.
Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain. Native ferritin from human liver. Sterile-filtered.
Zastosowanie
Ferritin is suitable for use in immunofluorescence assay, immunoassays, as an immunogen, and in enzyme/radiolabeling.
Działania biochem./fizjol.
Ferritin is a crucial protein that has multiple functions in iron metabolism and immune regulation. It helps in maintaining the iron balance. H-ferritin is involved in various processes such as regulating immune function, hematopoiesis, hepatocyte apoptosis, and cell differentiation. Additionally, ferritin can act as a proinflammatory cytokine through protein kinase C-zeta (PKC-ζ) and nuclear factor kappa B (NFκB) signaling pathways in certain cells.(1) Ferritin serves as both an immune-suppressor and a signaling molecule, contributing to the regulation of lymphoid and myeloid cell proliferation.
Opakowanie
Please refer to vial label for lot-specific concentration.
Ostrzeżenie
Toxicity: Standard Handling (A)
Postać fizyczna
In 0.9% NaCl, 0.1% NaN₃, pH 7.0.
Inne uwagi
Addison, J.M., et al. 1983. FEBS Lett.164, 139.
Informacje prawne
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
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New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity
Recalcati S, et al.
Journal of Autoimmunity, 30(1-2), 84-89 (2008)
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells
Ruddell RG, et al.
Journal of Separation Science, 49(3), 887-900 (2009)
Ferritin, iron homeostasis, and oxidative damage
Arosio P and Levi S
Free radical biology & medicine, 33(4), 457-463 (2002)
Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells
Ruddell RG, et al.
Hepatology, 49(3), 887-900 (2009)
Ferritin, iron homeostasis, and oxidative damage
Arosio P, et al.
Journal of Separation Science, 33(4), 457-463 (2002)
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