250225

Cytochalasin B, Dihydro-

Induces changes in cell morphology and motility with no effect on sugar transport.

• Synonim(y): Cytochalasin B, Dihydro-
• Wzór empiryczny (zapis Hilla): C₂₉H₃₉NO₅
• Numer CAS: 39156-67-7
• Masa cząsteczkowa: 481.62
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD12910542
• Assay: ≥98% (TLC)
• Form: solid
• Quality level: 100
• Storage condition: OK to freeze, protect from light

Właściwości

• Quality Level: 100
• description: Merck USA index - 14, 2790
• assay: ≥98% (TLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: methanol: 10 mg/mL, ethanol: 2 mg/mL, DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: N1[C@H]([C@H]3[C@@]4(OC(=O)CC[C@@H](CCC[C@H](C\C=C\[C@H]4[C@@H](C(=C)[C@H]3C)O)C)O)C1=O)Cc2ccccc2
• InChI: 1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1
• InChI key: WIULKAASLBZREV-RXPQEOCGSA-N

Opis

General description

Induces changes in cell morphology and motility with no effect on sugar transport. Used as a specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Changes in cell morphology and motility

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Lin, D.C., and Lin, S. 1978. J. Biol. Chem.253, 1415.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300 + H310 + H330,H351
• pcodes: P202 - P260 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable