239900

Cypermethrin

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

• Synonim(y): Cypermethrin
• Wzór empiryczny (zapis Hilla): C₂₂H₁₉Cl₂NO₃
• Numer CAS: 52315-07-8
• Masa cząsteczkowa: 416.30
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00055328
• Assay: ≥95% (HPLC)
• Form: oil
• Quality level: 100
• Storage condition: OK to freeze

Właściwości

• description: Merck USA index - 14, 2767
• Quality Level: 100
• assay: ≥95% (HPLC)
• form: oil
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: DMSO: 15 mg/mL, ethanol: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: ClC(=CC1C(C1C(=O)OC(c2cc(ccc2)Oc3ccccc3)C#N)(C)C)Cl
• InChI: 1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
• InChI key: KAATUXNTWXVJKI-UHFFFAOYSA-N

Opis

General description

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC₅₀ = 40 pM). May also have varied effects on ion channels.

Biochem/physiol Actions

Primary Target
calcineurin

Product does not compete with ATP.

Target IC₅₀: 40 pM against calcineurin (protein phosphatase 2B

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.
Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.
Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.
Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Toxic (F)

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302 + H332,H315,H317,H335,H373,H410
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
• target_organs: Nervous system, Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: 212.0 °F - closed cup
• flash_point_c: 100 °C - closed cup