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217503

Cardiotoxin

from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®

Synonim(y):

Cardiotoxin, Naja pallida

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Informacje o tej pozycji

Numer CAS:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.32
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze
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Nazwa produktu

Cardiotoxin, Naja pallida,

description

Merck USA index - 14, 1835

Quality Level

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.

Application

Cardiotoxin, Naja pallida has been used:
  • to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration
  • to induce a skeletal muscle injury into the right TA muscle
  • to induce muscle regeneration

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.

Legal Information

Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)
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Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
Samani A, et al.
bioRxiv : the preprint server for biology (2023)
Snake peptides
Harvey, Alan L
Handbook of Biologically Active Peptides (2013)
Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice
Chen J, et al.
Cell Death & Disease, 15(3), 201-201 (2024)
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy
Matias-Valiente L, et al.
Biomedicine and Pharmacotherapy, 170, 116056-116056 (2024)
Valeria Yartseva et al.
Cell reports, 30(5), 1491-1503 (2020-02-06)
How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell fate decisions has been the difficulty of studying this process in vivo. By visualizing expression

Numer pozycji handlu globalnego

SKUNUMER GTIN
217503-1MG04055977276800

Questions

1–2 of 2 Questions  
  1. What is the suggested storage life of the lyophilized powder at 4C, -20C, and -80C? What about reconstituted powder at -80?

    1 answer
    1. In lyophilized powder format, this product should be stored at 2-8°C. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. The stability of solutions stored at -80°C has not been determined.

      Helpful?

  2. Re 217503 Cardiotoxin, Naja pallida - could you please ask your supplier for more details on this protein: which form of 3FTx is it ? Can they give me an accession number or a UniProt entry, thanks.

    1 answer
    1. This product is classified as Cytotoxin 1. The UniProt accession number is P01468. Please see the link below to review the UniProt profile:
      https://www.uniprot.org/uniprotkb/P01468/entry

      Helpful?

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