Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

12-457

MYPT1 (654-880)

Name: MYPT1 (654-880)
Brand: MM

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Informacje o tej pozycji

UNSPSC Code:

12352200

NACRES:

NA.41

eCl@ss:

32160405

Form:

liquid

Assay:

≥70% (Coomassie staining, SDS-PAGE)

Ten produkt nie jest już w sprzedaży. Skontaktuj się z zespołem ds. pomocy technicznejdla wsparcia

assay

≥70% (Coomassie staining, SDS-PAGE)

form

liquid

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002480.1

UniProt accession no.

O14974

shipped in

dry ice

Gene Information

human ... PPP1R12A(4659)

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja	SRP0205	SRP0454	SRP0451
Sigma-Aldrich 12-457 MYPT1 (654-880)	Sigma-Aldrich SRP0205 MEG-1 Active human	Sigma-Aldrich SRP0454 BRD2, BD1, BD2 (65-459) GST tag human	Sigma-Aldrich SRP0451 BRD2 (65-187) GST tag human
technique(s) activity assay: suitable (kinase)	technique(s) -	technique(s) -	technique(s) -
assay ≥70% (Coomassie staining, SDS-PAGE)	assay ≥90% (SDS-PAGE)	assay ≥80% (SDS-PAGE)	assay ≥81% (SDS-PAGE)
form liquid	form aqueous solution	form aqueous solution	form aqueous solution
UniProt accession no. O14974	UniProt accession no. P29074	UniProt accession no. P25440	UniProt accession no. P25440
Gene Information human ... PPP1R12A(4659)	Gene Information human ... PTPN4(5775)	Gene Information human ... BRD2(6046)	Gene Information human ... BRD2(6046)
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in dry ice

General description

Product Source: expressed in E. coli

ROK substrate protein corresponding to amino acids 654-880 of human MYPT1 with an N-terminal GST tag. MW = 60 kDa.

Biochem/physiol Actions

Protein Target: myosin phosphatase

Physical form

100mM Tris-HCl pH 8.0, 200mM NaCl, 10mM glutathione and 5μg/ml leupeptin. Frozen solution.

Preparation Note

1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery, centrifuge the vial prior to removing the cap.

Analysis Note

Routinely evaluated as a substrate in a Protein Kinase Assay.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ta strona może zawierać tekst przetłumaczony maszynowo.

pictograms

GHS08

signalword

Danger

hcodes

H334

pcodes

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation.

G Totsukawa et al.

The Journal of cell biology, 144(4), 735-744 (1999-02-26)

It has been demonstrated previously that during mitosis the sites of myosin phosphorylation are switched between the inhibitory sites, Ser 1/2, and the activation sites, Ser 19/Thr 18 (Yamakita, Y., S. Yamashiro, and F. Matsumura. 1994. J. Cell Biol. 124:129-

Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase.

J Feng et al.

The Journal of biological chemistry, 274(52), 37385-37390 (1999-12-22)

It is clear from several studies that myosin phosphatase (MP) can be inhibited via a pathway that involves RhoA. However, the mechanism of inhibition is not established. These studies were carried out to test the hypothesis that Rho-kinase (Rho-associated kinase)

Extracellular matrix controls insulin signaling in mammary epithelial cells through the RhoA/Rok pathway.

Yi-Ju Lee et al.

Journal of cellular physiology, 220(2), 476-484 (2009-04-25)

Cellular responses are determined by a number of signaling cues in the local microenvironment, such as growth factors and extracellular matrix (ECM). In cultures of mammary epithelial cells (MECs), functional differentiation requires at least two types of signal, lactogenic hormones

Numer pozycji handlu globalnego

SKU	NUMER GTIN
12-457	04053252625183
BAH131781218-100EA	04065269240235
BAH131761218-100EA	04065269240099

Questions

Reviews

No rating value

Active Filters

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej