09-838
Anti-Histone H3.3 (H3-3A,H3-3B) Antibody
rabbit polyclonal
Synonim(y):
Histon H3.3
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μg | Przewidywany termin wysyłki27 maja 2026zKuehne + Nagel Sp. z o.o. | 2370,00 zł |
Informacje o tej pozycji
2370,00 zł
Przewidywany termin wysyłki27 maja 2026Szczegóły
Nazwa produktu
Przeciwciało anty-histonowe H3.3, from rabbit, purified by affinity chromatography
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
technique(s)
ChIP: suitable, dot blot: suitable, immunocytochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... H3F3B(3021)
General description
Immunogen
Application
Zdjęcie dzięki uprzejmości Simona Elsässera z Laboratorium Davida Allisa, Uniwersytet Rockefellera, Nowy Jork.
Analiza immunoprecypitacji chromatyny: Reprezentatywna partia została wykorzystana przez niezależne laboratorium w ChIP.
Zdjęcie dzięki uprzejmości Simona Elsässera z David Allis′ Laboratory, Rockefeller University, Nowy Jork.
Analiza Dot Blot: Reprezentatywna partia została wykorzystana przez niezależne laboratorium w DB.
Zgłoszone przez Simona Elsässera, Laboratorium dr Davida Allisa, Uniwersytet Rockefellera, Nowy Jork.
Epigenetyka i funkcje jądrowe
Histony
Biochem/physiol Actions
Physical form
Preparation Note
Analysis Note
Western Blot Analysis: 1 µg/mL of this antibody detected Histone H3.3 on 10 µg of HeLa acid extract.
Ekstrakt kwasu HeLa
Other Notes
Disclaimer
1 of 1
Ta pozycja | |||
|---|---|---|---|
| species reactivity mouse, human | species reactivity mouse, rat, human | species reactivity human | species reactivity human |
| clone polyclonal | clone polyclonal | clone MC463, monoclonal | clone 3H10, monoclonal |
| biological source rabbit | biological source rabbit | biological source rabbit | biological source mouse |
| antibody form affinity isolated antibody | antibody form purified antibody | antibody form culture supernatant | antibody form purified immunoglobulin |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| Gene Information human ... H3F3B(3021) | Gene Information human ... H3C1(8350) | Gene Information human ... HIST1H3F(8968) | Gene Information human ... H3C1(8350) |
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Powiązane treści
Histone Modifications Poster
New Products: Antibodies, Assays, Small Molecules, Inhibitors, and Proteins
Cancer is a complex disease manifestation. At its core, it remains a disease of abnormal cellular proliferation and inappropriate gene expression. In the early days, carcinogenesis was viewed simply as resulting from a collection of genetic mutations that altered the gene expression of key oncogenic genes or tumor suppressor genes leading to uncontrolled growth and disease (Virani, S et al 2012). Today, however, research is showing that carcinogenesis results from the successive accumulation of heritable genetic and epigenetic changes. Moreover, the success in how we predict, treat and overcome cancer will likely involve not only understanding the consequences of direct genetic changes that can cause cancer, but also how the epigenetic and environmental changes cause cancer (Johnson C et al 2015; Waldmann T et al 2013). Epigenetics is the study of heritable gene expression as it relates to changes in DNA structure that are not tied to changes in DNA sequence but, instead, are tied to how the nucleic acid material is read or processed via the myriad of protein-protein, protein-nucleic acid, and nucleic acid-nucleic acid interactions that ultimately manifest themselves into a specific expression phenotype (Ngai SC et al 2012, Johnson C et al 2015). This review will discuss some of the principal aspects of epigenetic research and how they relate to our current understanding of carcinogenesis. Because epigenetics affects phenotype and changes in epigenetics are thought to be key to environmental adaptability and thus may in fact be reversed or manipulated, understanding the integration of experimental and epidemiologic science surrounding cancer and its many manifestations should lead to more effective cancer prognostics as well as treatments (Virani S et al 2012).