03-0187-00

Zestaw do wysokoczułego testu immunologicznego ^® Human MCP-1

Used for ultrasensitive quantification of Human MCP-1 in human serum and plasma

• Synonim(y): Ultraczuły test immunologiczny MCP-1, Zestaw do liczenia pojedynczych cząsteczek MCP-1, Zestaw do testu immunologicznego MCP 1, Zestaw do testu immunologicznego monocytarnego białka chemoatrakcyjnego-1
• NACRES: NA.84
• UNSPSC Code: 12161503
• Species reactivity: human
• Technique(s): single molecule counting: suitable
• Usage: kit sufficient for 96 wells
• Compatibility: for use with FemtoQuest^™ and SMCxPRO^® instruments

Właściwości

• Nazwa produktu: Zestaw do wysokoczułego testu immunologicznego ^® Human MCP-1,
• description: Used for ultrasensitive quantification of Human MCP-1 in human serum and plasma
• product line: SMC^®
• usage: kit sufficient for 96 wells
• species reactivity: human
• technique(s): single molecule counting: suitable
• input: plasma (K2 EDTA); serum
• UniProt accession no.: P13500
• compatibility: for use with FemtoQuest^™ and SMCxPRO^® instruments
• shipped in: wet ice
• storage temp.: 2-8°C

Opis

General description

Monocyte Chemoattractant Protein-1 (MCP-1), also known as CCL2, is a chemokine that plays a critical role in the recruitment of monocytes to sites of inflammation and injury. It is produced by various cell types, including macrophages, endothelial cells, and fibroblasts, in response to inflammatory stimuli. MCP-1 is involved in several physiological and pathological processes, including atherosclerosis, chronic inflammatory diseases, and tissue repair.

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

• Breakthrough-level sensitivity for translational research: Supports early-stage biomarker identification and immune profiling with unmatched precision.
• Wide Quantification Range: Captures MCP-1 levels across both baseline and elevated inflammatory states, ideal for diverse sample types.
• Streamlined ELISA Workflow with SMC^® Enhancements: Uses a familiar sandwich immunoassay format with a unique elution step for digital molecule counting.
• Illuminate Monocyte Migration Pathways: MCP-1 is a key chemokine in immune cell recruitment; this kit helps quantify its role in inflammation and tissue infiltration.

Packaging

96 well assay

Analysis Note

• Sensitivity: LLOQ 150 fg/mL* (SMCxPRO^® Instrument)
• Standard Curve Range: 80-400,000 fg/mL
• Intra-assay CV: <15%
• Inter-assay CV: <20%
• Linearity: Serum: 102% Plasma: 94%
• Recovery: Serum: 104% Plasma: 101%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.

Other Notes

MCP-1 was not cross-reactive with rat, mouse, or canine samples.

Legal Information

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

O ile nie określono inaczej w naszym katalogu lub innej dokumentacji firmy dołączonej do produktu(-ów), nasze produkty są przeznaczone wyłącznie do użytku badawczego i nie mogą być wykorzystywane do żadnych innych celów, w tym między innymi do nieautoryzowanych zastosowań komercyjnych, zastosowań diagnostycznych in vitro, zastosowań terapeutycznych ex vivo lub in vivo lub jakiegokolwiek rodzaju konsumpcji lub zastosowania u ludzi lub zwierząt.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08
• signalword: Danger
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• hcodes: H302 + H332,H311,H319,H360FD,H412,EUH430
• pcodes: P201 - P202 - P273 - P280 - P308 + P313 - P391 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B