1500003

Siarczan paromomycyny

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Paromomycin sulfate salt, Aminosidine sulfate
• Wzór empiryczny (zapis Hilla): C₂₃H₄₅N₅O₁₄ · xH₂SO₄
• Numer CAS: 1263-89-4
• Masa cząsteczkowa: 615.63 (free base basis)
• MDL number: MFCD29505371
• UNSPSC Code: 41116107
• NACRES: NA.24

Właściwości

• grade: pharmaceutical primary standard
• API family: paromomycin
• form: solid
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: [S](=O)(=O)(O)O.N[C@H]1[C@H](O[C@H]([C@H]([C@@H]1O)O)CN)O[C@@H]2[C@H](OC([C@@H]2O)O[C@@H]3[C@H]([C@@H](C[C@@H](C3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO)N)N)O)CO
• InChI: 1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;/m1./s1
• InChI key: LJRDOKAZOAKLDU-UMIPPVEZSA-N

Opis

General description

Paromomycin sulfate is an aminoglycoside antibiotic primarily used in the treatment of parasitic infections and certain bacterial infections. It inhibits protein synthesis at the 30S ribosomal subunit. The USP reference standard is employed in potency and identity assays.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Wzorzec referencyjny siarczanu paromomycyny USP służy do przygotowywania roztworów wzorcowych do identyfikacji i oznaczania siarczanu paromomycyny.
Również do użytku z monografiami USP, takimi jak:

• Siarczan paromomycyny kapsułki
• Roztwór doustny paromomycyny

Other Notes

Ten produkt jest częścią programu USP Biologics.

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable