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1012780

USP

Alendronian sodu

Name: Alendronian sodu
Brand: USP
Price: 1940 PLN

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

Alendronate sodium trihydrate, 4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium, MK-217

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Gabaryty przesyłki	SKU	Dostępność	Cena netto
200 mg		Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności	1940,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₄H₁₂NaNO₇P₂ · 3 H₂O

Numer CAS:

121268-17-5

Masa cząsteczkowa:

325.12

NACRES:

NA.24

PubChem Substance ID:

329748953

UNSPSC Code:

41116107

MDL number:

MFCD01748233

1940,00 zł

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Właściwości

grade

pharmaceutical primary standard

agency

USP

API family

alendronate

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O

InChI

1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1

InChI key

DCSBSVSZJRSITC-UHFFFAOYSA-M

Gene Information

human ... FDPS(2224)

Opis

General description

Alendronate sodium is a primary amino bisphosphonate.[1]

Application

Alendronate sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Alendronate sodium trihydrate is a bone resorption inhibitor; farnesyl diphosphate synthase inhibitor (IC₅₀= 460 nM); CD45 protein tyrosine phosphatase inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Ta pozycja	Y0001727	BP830	PHR1599
USP 1012780 Alendronate sodium	Y0001727 Sodium alendronate trihydrate	BP830 Sodium alendronate	Supelco PHR1599 Alendronate Sodium
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)
API family alendronate	API family alendronate	API family alendronate	API family alendronate

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Ghrelin against alendronate-induced gastric damage in rats.

S O Işeri et al.

The Journal of endocrinology, 187(3), 399-406 (2006-01-21)

Alendronate sodium, a primary amino bisphosphonate, is widely used in the treatment of various diseases that are associated with bone resorption, such as postmenopausal osteoporosis and Paget's disease of bone. Although the adverse effects of biphosphonates on the gastrointestinal system

Single and combined effect of high-frequency loading and bisphosphonate treatment on the bone micro-architecture of ovariectomized rats.

K Hatori et al.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 26(1), 303-313 (2014-09-23)

Mechanical loading at high frequency affects bone. Whether this also applies to osteoporotic bone, combined or not with bisphosphonate therapy, was investigated in this animal study through imaging. An anabolic effect of high-frequency loading on osteoporotic bone, however non-synergistic with

The effect of alendronate-loaded polycarprolactone nanofibrous scaffolds on osteogenic differentiation of adipose-derived stem cells in bone tissue regeneration.

Young-Pil Yun et al.

Journal of biomedical nanotechnology, 10(6), 1080-1090 (2014-04-23)

The osteogenic effect of culturing adipose-derived stem cells (ADSCs) on alendronate (Aln)-loaded polycarprolactone (PCL) nanofibrous scaffolds was evaluated by examining alkaline phosphatase (ALP) activity, calcium content, and expression of osteogenic differentiation genes in vitro. The 10% Aln/PCL nanofibrous scaffolds showed

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Numer pozycji handlu globalnego

SKU	NUMER GTIN
1012780-200MG	04061838667496

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