T9250

Thymidine

≥99%, synthetic (organic), powder

• Synonim(y): 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT
• Wzór empiryczny (zapis Hilla): C₁₀H₁₄N₂O₅
• Numer CAS: 50-89-5
• Masa cząsteczkowa: 242.23
• NACRES: NA.51
• PubChem Substance ID: 24900588
• UNSPSC Code: 41106305
• EC Number: 200-070-4
• MDL number: MFCD00006537
• Beilstein/REAXYS Number: 89285
• Assay: ≥99%
• Biological source: synthetic (organic)
• Form: powder
• Solubility: water: 50 mg/mL, clear, colorless

Właściwości

• Nazwa produktu: Thymidine, ≥99%
• biological source: synthetic (organic)
• Quality Segment: 300
• assay: ≥99%
• form: powder
• mp: 186-188 °C (lit.)
• solubility: water: 50 mg/mL, clear, colorless
• SMILES string: CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
• InChI: 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
• InChI key: IQFYYKKMVGJFEH-XLPZGREQSA-N
• Gene Information: human ... DTYMK(1841)

Opis

General description

Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine. It is useful in cell synchronization during S-phase. In the salvage pathway of pyrimidines, pyrimidine phosphorylase reversibly converts thymine to thymidine.

Application

Thymidine has been used:

• as a supplement in HL5-modified medium for cell culture[1]
• to incubate cells in cell-cycle analysis
• in cell synchronization

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)