SRP4388

SDF-1alpha (CXCL12) from mouse

recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC)

• Synonim(y): CXCL12, PBSF, Pre-B cell growth-stimulating factor, SDF-1, chemokine (C-X-C motif) ligand 12, hIRH
• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD01867605

Właściwości

• biological source: mouse
• recombinant: expressed in E. coli
• assay: ≥99% (HPLC), ≥99% (SDS-PAGE)
• form: lyophilized
• potency: 50-100 ng/mL
• mol wt: ~7.9 kDa
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• NCBI accession no.: P40224
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Sdf1(20315)

Opis

General description

Stromal Cell-Derived Factor-1α (SDF-1α) is a recently discovered protein belonging to the α-chemokine (C-X-C) family of cytokines. Recombinant mouse SDF-1α is a 7.9kDa protein containing 68 amino acids residues.

Biochem/physiol Actions

Stromal Cell-Derived Factor-1α (SDF-1α) is a pleiotropic chemokine. It works as a chemoattractant for T- and B-lymphocytes and inflammatory monocytes. In neural stem cells, SDF-1α is needed for proliferation, survival, migration, intercellular interaction and guidance to neuronal axon. It is responsible for pathogenic inflammation in the central nervous system (CNS).[1] It also controls BMP (bone morphogenic protein)-associated osteogenic differentiation.

Physical form

Lyophilized from 10 mM acetic acid. The protein may appear as a haze or film, which is difficult to see at the bottom of the vial.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitution in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable