SBNMQ

NMQ/N-methyl-quinidine - MDR1/P-gp Substrate

• Synonim(y): SB-NMQ, N-methyl-quinidine (NMQ), NMQ
• Wzór empiryczny (zapis Hilla): C₂₁H₂₇IN₂O₂
• Numer CAS: 42982-87-6
• Masa cząsteczkowa: 466.36
• UNSPSC Code: 12352200
• NACRES: NA.84
• Form: powder

Właściwości

• form: powder
• color: white
• storage temp.: room temp
• SMILES string: [I-].[N+]21([C@H](CC([C@H](C2)C=C)CC1)[C@@H](O)c3c4c(ncc3)ccc(c4)OC)C
• InChI: 1S/C21H27N2O2.HI/c1-4-14-13-23(2)10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-3)12-18(17)19;/h4-7,9,12,14-15,20-21,24H,1,8,10-11,13H2,2-3H3;1H/q+1;/p-1/t14-,15?,20+,21-,23?;/m0./s1
• InChI key: AJQSDVGBERUTGX-QVEQJUGRSA-M

Opis

Application

NMQ/N-methyl-quinidine - MDR1/P-gp substrate has been used as a probe substrate for multidrug resistance protein 1 (MDR1) in vesicles assay.

Biochem/physiol Actions

SOLVO Biotechnology offers NMQ as a selective substrate for the MDR1 membrane transporter.

NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable