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R5381

Anti-Rat IgG (whole molecule) antibody produced in rabbit

whole antiserum

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Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), QPA
Citations:
2


biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 2.8 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG) is made up of four polypeptide chains: two heavy chains (γ chains) and two light chains (κ or λ chains) which are inter linked by disulfide bonds. The Fab (fragment antigen binding) arm of IgG is formed by the VH and CH1 domains of the heavy and the light chains. The V regions of the antibody serve as the antigen-binding region. IgG class of immunoglobulins consists of four sub-classes i.e IgG1, IgG2, IgG3, and IgG4.. T

Biochem/physiol Actions

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) is a group of antibodies that are involved in modulating various immune responses. IgG activates the complement system and regulates the antibody-dependent cell-mediated cytotoxicity (ADCC).

Physical form

Rabbit Anti-Rat IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as preservative.

Preparation Note

treated to remove lipopro­teins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja
R9255G5518G4018
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 2.8 mg/mL

technique(s)

indirect ELISA: 1:100,000, quantitative precipitin assay: 2.5-5 mg/mL

technique(s)

indirect ELISA: 1:50,000, quantitative precipitin assay: 3.5 mg/mL

technique(s)

indirect ELISA: 1:60,000, quantitative precipitin assay: 2.0 mg/mL

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

antibody form

affinity isolated antibody

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal


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Klasa składowania

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Powiązane treści


Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG



Numer pozycji handlu globalnego

SKUNUMER GTIN
R5381-2ML04061836695606

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