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N5912

Anti-NORE1 (RASSF5) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonim(y):

Anti-RAPL, Anti-Ras Association (RalGDS/AF-6) Domain Family 5

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Gabaryty przesyłkiSKUDostępnośćCena netto
100 μg
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2410,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
5

2410,00 zł


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human

technique(s)

western blot: 1:500-1:1,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RASSF5(83593)
mouse ... Rassf5(54354)
rat ... Rassf5(54355)

General description

Ras association domain family member 5 (RASSF5) is also known as novel Ras effector- 1 (NORE-1). It exists in three isoforms and the gene encoding it is located on human chromosome 1q32.1.

Immunogen

peptide corresponding to the NORE1 protein (amino acids 313-329). This sequence is located in the RA domain of NORE1 and is 100% conserved between human, mouse, rat, and hamster.

Biochem/physiol Actions

Ras association domain family member 5 (RASSF5) is a tumor suppressor protein. It interacts with kinases like mammalian sterile 20-like kinase 1/2 (MST1/2). RASSF5 is involved in the regulation of cell cycle and apoptosis.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja
SAB1409867SAB1408065SAB2500871
Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

goat

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

western blot: 1:500-1:1,000

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

western blot: 1 μg/mL

technique(s)

indirect ELISA: suitable, western blot: suitable

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice


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Klasa składowania

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Powiązane treści


Xu-Hui Zhou et al.
Oncology reports, 32(4), 1505-1512 (2014-08-12)
Ras association (RalGDS/AF-6) domain family member RASSF5 has been implicated in a variety of key biological processes, including cell proliferation, cell cycle regulation and apoptosis. It is believed to play an important role in tumorigenesis as a tumor suppressor in
Katherine K Slemmons et al.
Cancer research, 80(14), 3046-3056 (2020-05-02)
Rhabdomyosarcoma is the most common childhood soft-tissue sarcoma, yet patients with metastatic or recurrent disease continue to do poorly, indicating a need for new treatments. The SRC family tyrosine kinase YES1 is upregulated in rhabdomyosarcoma and is necessary for growth
Xiaoli Liu et al.
Frontiers in oncology, 10, 600927-600927 (2021-01-26)
The principal issue derived from thyroid cancer is its high propensity to metastasize to the lymph node. Aberrant exprssion of long non-coding RNAs have been extensively reported to be significantly correlated with lymphatic metastasis of thyroid cancer. However, the clinical



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SKUNUMER GTIN
N5912-100UG04061838071736

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