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I6784
Monoclonal Anti-Interleukin-2 antibody produced in mouse
clone 5334, purified immunoglobulin, lyophilized powder
Synonim(y):
Anti-IL2, Anti-Lymphokine, Anti-TCGF
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 500 μg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 4360,00 zł |
Informacje o tej pozycji
NACRES:
NA.41
UNSPSC Code:
51111800
Conjugate:
unconjugated
Clone:
5334, monoclonal
Application:
FACS, IHC, Neutral
Citations:
5
4360,00 zł
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Pomoc techniczna
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Pozwól nam pomócbiological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5334, monoclonal
form
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: 25 μg/mL, immunohistochemistry: 8-25 μg/mL, neutralization: suitable
isotype
IgG1
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IL2(3558)
General description
Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It does not react with mouse IL-2.
Monoclonal Anti-Interleukin-2 recognizes human Interleukin-2. It does not react with mouse IL-2.
Immunogen
purified, E. coli-derived recombinant human interleukin-2.
Application
Anti-interleukin-2 antibody may be used in immunohistochemistry at a working concentration of 8-25 μg/ml in human peripheral blood leukocytes. For flow cytometry a concentration of 25 μg/ml may be used. The antibody is suitable for IL-2 neutralization assays.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Ta pozycja | |||
|---|---|---|---|
| antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form IgG fraction of antiserum | antibody form purified immunoglobulin |
| clone 5334, monoclonal | clone 6708.11, monoclonal | clone polyclonal | clone 3C8, monoclonal |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| species reactivity human | species reactivity human | species reactivity human | species reactivity human |
| biological source mouse | biological source mouse | biological source goat | biological source mouse |
| Gene Information human ... IL2(3558) | Gene Information human ... IL6(3569) | Gene Information human ... IL2(3558) | Gene Information human ... IL2(3558) |
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Klasa składowania
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Powiązane treści
Instructions
B H Nelson et al.
Advances in immunology, 70, 1-81 (1998-10-02)
Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current understanding of immunology. Chief among these is the contribution made by lymphokines to regulation of the
Matthew A Williams et al.
Nature, 441(7095), 890-893 (2006-06-17)
Although interleukin-2 (IL-2) was initially characterized as the primary T-cell growth factor following in vitro activation, less is known about its role in shaping T-cell responses to acute infections in vivo. The use of IL-2- or IL-2-receptor-deficient mice is problematic
Katrina K Hoyer et al.
Immunological reviews, 226, 19-28 (2009-01-24)
Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T-cell proliferation and T-helper 1 (Th1) and Th2 effector T-cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| I6784-500UG | 04061832714646 |