The buffers used during the purification process of this product range from a neutral pH up to pH 8.3. No acidic buffers are used during processing.
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H3536
Haptoglobin from pooled human plasma
≥95% (SDS-PAGE), lyophilized powder
Synonim(y):
Haptoglobin from human plasma
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 1 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1010,00 zł | |
| 5 mg | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 3480,00 zł |
Informacje o tej pozycji
Form:
lyophilized powder
Assay:
≥95% (SDS-PAGE)
Biological source:
human plasma (pooled)
1010,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócGeneral description
Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins.The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains.
Haptoglobin is an acute phase protein that scavenges hemoglobin released into the circulation. Haptoglobin, the plasma protein with highest binding affinity to hemoglobin, is mainly expressed in the liver.[1]
Application
Haptoglobin was used to study induction of the acrosome reaction in sperm. Exposure to low temperature increases their rate of fusion with zona-free hamster oocytes.[2]
Biochem/physiol Actions
Functions by binding to plasma hemoglobin (from hemolysis). The complex is removed from the circulation, by binding to CD163 receptors on macrophages, to salvage iron and prevent oxidative damage.
Other Notes
Occurs as 3 major phenotypes: type 1-1, type 2-1, type 2-2.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Ta pozycja | |||
|---|---|---|---|
| technique(s) activity assay: suitable | technique(s) immunoelectrophoresis: suitable, immunoprecipitation (IP): suitable | technique(s) - | technique(s) - |
| biological source human plasma (pooled) | biological source human plasma | biological source - | biological source human |
| assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay >95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) |
| form lyophilized powder | form lyophilized powder | form lyophilized | form lyophilized |
| solubility H2O: soluble 10 mg/mL | solubility H2O: soluble 1 mg/mL | solubility physiological buffer: soluble | solubility - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Powiązane treści
R Sanchez et al.
International journal of andrology, 14(6), 423-430 (1991-12-01)
The fusion rate of human sperm with zona-free hamster ova was investigated after induction of the acrosome reaction by exposure to a low temperature (4 degrees C). Sperm were collected from 14 patients, and selected by the 'swim-up' method. The
Eiko Shimada et al.
Transfusion, 47(12), 2315-2321 (2007-09-04)
Congenital haptoglobin deficiency is a risk factor for anaphylactic nonhemolytic transfusion reactions in Japan. The deleted allele of the haptoglobin gene, Hp(del), which causes congenital haptoglobin deficiency, has also been observed in other Northeast Asian populations, such as Korean and
I B Ross et al.
Journal of neurotrauma, 8(4), 229-238 (1991-01-01)
Previously in our laboratory, nimodipine was effective in reversing posttraumatic ischemia and promoting electrophysiologic recovery in a rat spinal cord injury (SCI) model. However, these beneficial effects were achieved when nimodipine was combined with adjuvant therapy to reverse posttraumatic hypotension
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| H3536-5MG | 04061833793411 |
| H3536-1MG | 04061833793374 |
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H3536-1MG - I would like to know if this sample is ever exposed to acid buffer during preparation?
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