G7153

Guanidine hydrochloride

BioXtra, ≥99.5% (titration)

• Synonim(y): Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
• Wzór liniowy: NH₂C(=NH)NH₂ · HCl
• Numer CAS: 50-01-1
• Masa cząsteczkowa: 95.53
• EC Number: 200-002-3
• UNSPSC Code: 12352107
• PubChem Substance ID: 24895295
• Beilstein/REAXYS Number: 3591990
• MDL number: MFCD00013026

Właściwości

• product line: BioXtra
• assay: ≥99.5% (titration)
• impurities: Insoluble matter, passes filter test
• ign. residue: ≤0.05%
• loss: ≤0.05% loss on drying, HV, 20°C
• pH: 4.5-6.0 (6 M in H₂O)
• mp: 180-185 °C (lit.)
• solubility: H₂O: 6 M, clear, colorless
• density: 1.3 g/cm³ (lit.)
• anion traces: sulfate (SO₄^2-): ≤0.005%
• cation traces: Al: ≤0.0005%, As: ≤0.0001%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, Na: ≤0.005%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%
• absorption: ≤0.05 at 280 in H₂O at 6 M, ≤0.1 at 260 in H₂O at 6 M
• SMILES string: Cl[H].NC(N)=N
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• InChI key: PJJJBBJSCAKJQF-UHFFFAOYSA-N
• Gene Information: human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)

Opis

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H332,H315,H319
• pcodes: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable