E6888

Enalapril maleate salt

≥98.0% (HPLC), ACE inhibitor, powder

• Synonim(y): (S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt
• Wzór empiryczny (zapis Hilla): C₂₀H₂₈N₂O₅ · C₄H₄O₄
• Numer CAS: 76095-16-4
• Masa cząsteczkowa: 492.52
• UNSPSC Code: 12352200
• PubChem Substance ID: 24894639
• NACRES: NA.77
• EC Number: 278-375-7
• Assay: ≥98.0% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Enalapril maleate salt, powder, ≥98.0% (HPLC)
• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• form: powder
• color: white to off-white
• solubility: methanol: ≥50 mg/mL, clear, colorless to yellow
• originator: Merck & Co., Inc., Kenilworth, NJ, U.S.
• SMILES string: C[C@@H](C(N1[C@H](C(O)=O)CCC1)=O)N[C@H](CC(OCC)=O)CCC2=CC=CC=C2.O=C(OO)/C=C\C(O)=O
• InChI: 1S/C21H30N2O5.C4H4O5/c1-3-28-19(24)14-17(12-11-16-8-5-4-6-9-16)22-15(2)20(25)23-13-7-10-18(23)21(26)27;5-3(6)1-2-4(7)9-8/h4-6,8-9,15,17-18,22H,3,7,10-14H2,1-2H3,(H,26,27);1-2,8H,(H,5,6)/b;2-1-/t15-,17-,18-;/m0./s1
• InChI key: UQKQUZOIQFOJOI-KJHLASMFSA-N

Opis

General description

Enalapril is an angiotensin-converting enzyme inhibitor. It is used to treat heart failure and high blood pressure.

Application

Enalapril maleate salt has been used:

• to reduce albumin excretion rate (AER) and glomerular lesions
• to examine the effects of enalapril pre-treatment on myocardial injury
• to investigate its efficacious doses and schedules for mitigation of radiation lung injury[1]

Biochem/physiol Actions

A long-acting angiotensin-converting enzyme inhibitor.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08
• signalword: Warning
• hcodes: H361fd
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 2
• ppe: Eyeshields, Gloves, type N95 (US)