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C0244

CDK1/Cyclin A2, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonim(y):

CCN1, CCNA, CDC2, CDC28A, DKFZp686120222, MGC111195

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Gabaryty przesyłkiSKUDostępnośćCena netto
10 μg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
2280,00 zł

Informacje o tej pozycji

NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
151-205 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

2280,00 zł

Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomóc

recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

200

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

151-205 nmol/min·mg

mol wt

CDK1 subunit ~59 kDa, cyclin A2 ~78 kDa

UniProt accession no.

P06493, P20248

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CCNA2(890), CDK1(983)

Biochem/physiol Actions

CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
C1249SRP5009SRP5010
CDK1/Cyclin A2, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

C0244

CDK1/Cyclin A2, active, GST tagged human

CDK4/CyclinD3, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

C1249

CDK4/CyclinD3, active, GST tagged human

CDK1/CyclinB1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5009

CDK1/CyclinB1, active, GST tagged human

CDK2/CyclinA1, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5010

CDK2/CyclinA1, active, GST tagged human

Gene Information

human ... CCNA2(890), CDK1(983)

Gene Information

human ... CCND3(896), CDK4(1019)

Gene Information

human ... CCNB1(891), CDK1(983)

Gene Information

human ... CCNA1(8900), CDK2(1017)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

specific activity

151-205 nmol/min·mg

specific activity

13-19 nmol/min·mg

specific activity

12-16 nmol/min·mg

specific activity

70-95 nmol/min·mg

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

Klasa składowania

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
SLCD7338
SLBX2082
SLBW3287
SLBL2881V
SLBJ4989V

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Manas Seal et al.
The journal of physical chemistry. B, 125(47), 12947-12957 (2021-11-18)
Knowledge about the structural and dynamic properties of proteins that form membrane-less organelles in cells via liquid-liquid phase separation (LLPS) is required for understanding the process at a molecular level. We used spin labeling and electron paramagnetic resonance (EPR) spectroscopy
A C Rigas et al.
Oncogene, 26(55), 7611-7619 (2007-06-30)
Antiandrogens are initially effective in controlling prostate cancer (CaP), the second most common cancer in men, but resistance, associated with the loss of androgen-regulated cell cycle control, is a major problem. At present there is no effective treatment for androgen-independent
Carine Bossard et al.
PloS one, 7(9), e44787-e44787 (2012-09-13)
Ovarian cancer is the gynecological cancer exhibiting the highest morbidity and improvement of treatments is still required. Previous studies have shown that Estrogen-receptor beta (ERβ) levels decreased along with ovarian carcinogenesis. Here, we present evidence that reintroduction of ERβ in
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SKUNUMER GTIN
C0244-10UG04061837753169

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