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347M-1

Vimentin (V9) Mouse Monoclonal Antibody

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Informacje o tej pozycji

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
V9, monoclonal
Application:
IHC (p)
Citations:
10
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biological source

mouse

Quality Segment

100, 500

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

V9, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (347M-14), vial of 0.5 mL concentrate (347M-15), bottle of 1.0 mL predilute (347M-17), vial of 1.0 mL concentrate (347M-16), bottle of 7.0 mL predilute (347M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgGκ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... VIM(7431)

General description

Anti-vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. This antibody recognizes a 57 kD intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]
Vimentin Positive Control Slides, Product No. 347S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 2

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. What is the difference in concentration between the predilute versions and the concentrate versions? All of the concentrations on the COA are the same, which makes no sense.

    1 answer

    1. The protein or IgG concentration for the concentrate version should always be higher than that of the prediluted version.

      For example, In the case of the Vimentin (V9) sited, part # 347M-16 for the 1ml concentrate (lot # 0000414954) with a protein concentration of 42 ug/ml while part # 347M-18 for the 7ml predilute (lot # 0000365711) has a protein concentration of 0.27 ug/ml.

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