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130M-9

Sigma-Aldrich

CD30 (Ber-H2) Mouse Monoclonal Antibody

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About This Item

Kod UNSPSC:
12352203
NACRES:
NA.41

pochodzenie biologiczne

mouse

Poziom jakości

100
500

białko sprzężone

unconjugated

forma przeciwciała

culture supernatant

rodzaj przeciwciała

primary antibodies

klon

Ber-H2, monoclonal

opis

For In Vitro Diagnostic Use in Select Regions (See Chart)

Postać

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

vial of 0.1 mL concentrate (130M-94)
vial of 0.5 mL concentrate (130M-95)
bottle of 1.0 mL predilute (130M-97)
vial of 1.0 mL concentrate (130M-96)
bottle of 7.0 mL predilute (130M-98)

producent / nazwa handlowa

Cell Marque™

metody

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

izotyp

IgG1κ

kontrola

classic Hodgkin lymphoma

Warunki transportu

wet ice

temp. przechowywania

2-8°C

wizualizacja

membranous

informacje o genach

human ... TNFRSF8(943)

Opis ogólny

Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders, and in embryonal carcinomas. Occasionally diffuse large B-cell lymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissue. However, reactive immunoblasts are immunoreactive with this antibody. The staining pattern of anti-CD30 in lymphoma or embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.

Jakość


IVD
IVD
IVD
RUO

Powiązanie

CD30 Positive Control Slides, Product No. 130S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Uwaga dotycząca przygotowania

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Inne uwagi

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informacje prawne

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

R Schwarting et al.
Blood, 74(5), 1678-1689 (1989-10-01)
The production and characterization of a monoclonal antibody (MoAb) designated Ber-H2, directed against a new epitope of the Ki-1 (CD30) antigen, are described. In comparison with the formerly reported Ki-1 MoAb whose reactivity with Hodgkin and Reed-Sternberg (H-RS) cells in
Rabban JT, et al.
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 702-702 (2014)
David H George et al.
The American journal of surgical pathology, 27(4), 487-493 (2003-03-27)
Anaplastic large cell lymphoma (ALCL) rarely occurs in the central nervous system. Although defined by its composition of large, pleomorphic, CD30-positive lymphocytes, ALCL is heterogeneous. Most are T cell but some are null cell. Most but not all have a
Cyrus V Hedvat et al.
Human pathology, 33(10), 968-974 (2002-10-24)
The immunohistochemical analysis of lymphoid neoplasms has led to refined classification schemes based on the profile of antigen expression and correlation with morphological, cytogenetic, molecular, and clinical features. Tissue microarrays (TMAs) are a powerful tool to rapidly characterize the phenotypic

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