05130

L-Alanine

≥99.0% (NT)

• Synonim(y): (S)-2-Aminopropionic acid, L-α-Aminopropionic acid
• Wzór empiryczny (zapis Hilla): C₃H₇NO₂
• Numer CAS: 56-41-7
• Masa cząsteczkowa: 89.09
• Beilstein: 1720248
• Numer WE: 200-273-8
• Numer MDL: MFCD00064410
• Kod UNSPSC: 12352209
• eCl@ss: 32160406
• Identyfikator substancji w PubChem: 329747640
• NACRES: NA.26

Właściwości

• Próba: ≥99.0% (NT)
• Postać: powder or crystals
• aktywność optyczna: [α]20/D +14.0±1°, c = 5% in 5 M HCl
• zanieczyszczenia: ≤0.3% foreign amino acids
• pozostałość po prażeniu: ≤0.1% (as SO₄)
• strata: ≤0.1% loss on drying, 110 °C
• kolor: colorless to white
• mp: 314.5 °C
• rozpuszczalność: H₂O: soluble 89.1 g/l at 20 degrees c; diethyl ether: insoluble; ethanol: soluble (cold 80%)
• ślady anionów: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• ślady kationów: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; NH₄⁺: ≤100 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Zastosowanie: detection; peptide synthesis
• ciąg SMILES: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• Klucz InChI: QNAYBMKLOCPYGJ-REOHCLBHSA-N

Opis

Zastosowanie

L-Alanine is used as a standard to determine absolute concentration of a protein within a mixture of other proteins measured with SI traceability.

Działania biochem./fizjol.

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

L-alanine has the ability to promote the expression of ferritin and antioxidant stress proteins, heme oxygenase-1 (HO-1).

Uwaga dotycząca przygotowania

L-Alanine completely dissolves in water at a concentration of 89.1 g/l at 20°C to yield solution. It is also soluble in 80% ethanol and insoluble in ether.

Inne uwagi

Preparation of 2-chloropropionic acid; Reduction of derivatives to the aldehyde

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)