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Merck

F1427

Supelco

Florfenicol

analytical standard, for drug analysis

Synonim(y):

Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide

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About This Item

Wzór empiryczny (zapis Hilla):
C12H14Cl2FNO4S
Numer CAS:
Masa cząsteczkowa:
358.21
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

analytical standard, for drug analysis

Poziom jakości

Postać

solid

metody

HPLC: suitable
gas chromatography (GC): suitable

Zastosowanie

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

ciąg SMILES

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl

InChI

1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

Klucz InChI

AYIRNRDRBQJXIF-NXEZZACHSA-N

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Opis ogólny

Florfenicol is a broad-spectrum amphenicol antibiotic used against diseases affecting domestic and wild animals.

Zastosowanie

The analytical standard can be used as follows:
  • To measure florfenicol and its main metabolite florfenicol amine in tilapia meat by solid phase extraction (SPE) and ultra high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • Multi-residue analysis of three amfenicols in animal feed samples by HPLC-MS/MS method, following European Commission Decision 2002/657/EC(2)Determination of florfenicol in different animal feedstuff samples by thin layer chromatography (TLC) coupled with HPLC-UV detection
  • Residue analysis of florfenicol in broiler meat and liver samples by a reversed phase-HPLC method in combination with UV detection at 223 nm
  • Competitive indirect-chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) based quantitative analysis of florfenicol and its major metabolite florfenicol amine in chicken muscle samples, validated as per Commission Decision 2002/657/EC

Inne uwagi

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
This page may contain text that has been machine translated.

Piktogramy

Health hazardEnvironment

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1

Organy docelowe

Liver,Brain,Testes,Spinal cord,Blood,gallbladder

Kod klasy składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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Klienci oglądali również te produkty

Abdolhossein Jangaran Nejad et al.
Veterinary research forum : an international quarterly journal, 8(4), 327-331 (2018-01-13)
The aim of this study was to evaluate pharmacokinetic profiles of florfenicol after a single dose of intravenous (5.00 mg kg
Peizhen Li et al.
Frontiers in cellular and infection microbiology, 10, 369-369 (2020-09-10)
Bacterial resistance to antibiotics has become an important concern for public health. This study was aimed to investigate the characteristics and the distribution of the florfenicol-related resistance genes in bacteria isolated from four farms. A total of 106 florfenicol-resistant Gram-negative
Ye Wang et al.
Biosensors & bioelectronics, 87, 508-513 (2016-09-07)
Herein, a smart single-stranded DNA binding protein (SSB)-assisted fluorescence aptamer switch based on fluorescence resonance energy transfer (FRET) was designed. The FRET switch was synthesized by connecting SSB labeled quantum dots (QDs@SSB) as donor with aptamer (apt) labeled gold nanoparticles
Joren De Smet et al.
Frontiers in pharmacology, 9, 1265-1265 (2018-11-22)
Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described. Hence, the effect of various administration protocols
Chun-Liu Dong et al.
Frontiers in pharmacology, 8, 553-553 (2017-09-07)
Invasive infections due to

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