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59527

Silybin B

analytical standard

Synonim(y):

(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-hydroxymethyl-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone, (2S,3S)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-[(2R,3R)-3,5,7-trihydroxy-4-oxobenzopyran-2-yl]benzodioxin

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C25H22O10
Numer CAS:
Masa cząsteczkowa:
482.44
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:


grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤10.0% water, ≤3.0% residual solvents

application(s)

food and beverages

format

neat

SMILES string

COc1cc(ccc1O)[C@@H]2Oc3cc(ccc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O

InChI

1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1

InChI key

SEBFKMXJBCUCAI-WAABAYLZSA-N

General description

Silybin B is a flavonolignan present in silybin, an important bioactive constituent of silymarin extracted from the milk thistle plant, Silybum marianum. It is used in the treatment of various liver conditions and exhibits high anti-tumor promoting activity.[1]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Silybin B may be used as an analytical reference standard for the quantification of the analyte in milk thistle plant extract using liquid chromatography−electrospray tandem mass spectrometry.[1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.
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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Klasa składowania

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



James I Lee et al.
Journal of chromatography. A, 1116(1-2), 57-68 (2006-04-25)
A selective and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed for the characterization of silymarin in commercially available milk thistle extract. In this study, six main active constituents, including silydianin, silychristin, diastereomers of silybin (silybin A and
Kateřina Valentová et al.
International journal of molecular sciences, 19(8) (2018-08-12)
Silymarin, an extract from milk thistle (Silybum marianum) fruits, is consumed in various food supplements. The metabolism of silymarin flavonolignans in mammals is complex, the exact structure of their metabolites still remains partly unclear and standards are not commercially available.
Antonia Diukendjieva et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 53, 79-85 (2019-01-23)
In recent years the number of natural products used as pharmaceuticals, components of dietary supplements and cosmetics has increased tremendously requiring more extensive evaluation of their pharmacokinetic properties. This study aims at combining in vitro and in silico methods to



Numer pozycji handlu globalnego

SKUNUMER GTIN
59527-5MG04061833238202

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