49702

Carnosol

analytical standard

• Synonim(y): Picrosalvin
• Wzór empiryczny (zapis Hilla): C₂₀H₂₆O₄
• Numer CAS: 5957-80-2
• Masa cząsteczkowa: 330.42
• NACRES: NA.24
• PubChem Substance ID: 329757507
• UNSPSC Code: 85151701
• MDL number: MFCD02752467

Właściwości

• biological source: Rosemarinus officinalis L. leaves
• Quality Segment: 100
• grade: analytical standard
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): food and beverages
• format: neat
• storage temp.: −20°C
• SMILES string: CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
• InChI: 1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
• InChI key: XUSYGBPHQBWGAD-PJSUUKDQSA-N

Opis

General description

Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.

Carnosol is a naturally occurring phyto polyphenol[1]or phenolic diterpene[2], found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent[2] and anti-inflammatory agent.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A phenolic diterpene with antioxidant and anticarcinogenic activities.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: salvia

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P280 - P302 + P352
• Hazard Classifications: Skin Sens. 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable