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(R)-(−)-1-Aminoethylphosphonic acid

≥97.0% (NT)

Synonim(y):

L-(−)-1-Aminoethylphosphonic acid, L-Ala(P)

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Informacje o tej pozycji

Wzór liniowy:
CH3CH(NH2)P(O)(OH)2
Numer CAS:
Masa cząsteczkowa:
125.06
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4291032


assay

≥97.0% (NT)

optical activity

[α]20/D −4.8±0.5°, c = 5% in H2O

storage temp.

2-8°C

SMILES string

C[C@H](N)P(O)(O)=O

InChI

1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)/t2-/m1/s1

InChI key

UIQSKEDQPSEGAU-UWTATZPHSA-N

General description

(R)-(-)-1-Aminoethylphosphonic acid is a synthetic analog of L-alanine that shows antibacterial property.

Application

(R)-(−)-1-Aminoethylphosphonic acid can be used to prepare copper(II) heteroligand complexes, which are employed in the solution equilibrium studies.

Other Notes

Di- to tetrapeptides with this amino acid analogue at the "P-terminal" are bactericides and synergistic potentiators of penicillins and cephalophorins.[1][2][3]
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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Reaction of Alanine Racemase with 1-Aminoethylphosphonic Acid Forms a Stable External Aldimine
Stamper CGF, et al.
Biochemistry, 37(29), 10438-10445 (1998)
F R Atherton et al.
Antimicrobial agents and chemotherapy, 15(5), 677-683 (1979-05-01)
Peptide mimetics with C-terminal residues simulating natural amino acids have been designed as inhibitors of bacterial cell wall biosynthesis. The phosphonopeptide series consisting of various l and d residues of natural amino acids combined with 1-aminoalkyl (and aryl-alkyl-) phosphonic acid
J G Allen et al.
Antimicrobial agents and chemotherapy, 16(3), 306-313 (1979-09-01)
The metabolism and pharmacokinetics of a synthetic antibacterial phosphonodipeptide, alafosfalin, have been studied in rats, baboons, and human volunteers. The compound was rapidly absorbed from the injection site after subcutaneous and intramuscular administration and gave peak plasma concentrations at 15



Numer pozycji handlu globalnego

SKUNUMER GTIN
220817-25G04061838118608
220817-5G04061838118615

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